Chemometrics_annual_meeting_symposium.pdf
Time: 12.30 pm – 4.30 pm
Date: May 2nd, 2011
Place: Lecture room KB3B3, level 3 KBC building, Umeå University
Background: In the fields of proteomics and metabolomics the challenge of analyzing data from diverse platforms arises from its size, diversity and complexity. Understanding what information among all the variability in the data is is in itself a problem that needs evolving solutions.
Several mathematical and statistical methods have been developed for the analysis of chemical and biological data, resulting in different but overlapping disciplines such as bioinformatics, systems biology and chemometrics. Chemometrics in particular may be used during most phases of an experimental setup, from design of experiments, through data normalization and data-specific mathematical calculations, in order to allow one to visualize and summarize important information. This is achieved by using state-of-the-art methods for data exploration, calibration, discrimination and classification of data.
This symposium will focus on chemometrics applications in proteomics and metabolomics.
Scientific program
12:30 - 14:30h - Session A, chair Henrik Antti
Dr. Jenny Forshed, Karolinska Institute
-TBA
Dr. Pernilla Wikström, Umeå University
- "Metabolomics and proteomics to reveal biomarkers for aggressive prostate cancer"
Prof. Johan Gottfries, Gothenburg University
- "Anna Karenina's perspective on multivariate interpretation"
14:30 -15:00h - COFFEE BREAK
15:00 - 16:30h - Session B, chair Johan Trygg
Dr. Magnus Åberg, Stockholm University
- "Automated annotation and quantification of metabolites in 1H-NMR data of biological origin"
Dr. Anna Wuolikainen, Umeå University
- "Statistically you died yesterday"
Session I: Chairpersons Emma Andersson and Vladimir Vimberg |
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13.30-13.45 | Bacterial genes involved in macrophage TNF-alpha response to the human pathogen Streptococcus pyogenes Sophie Coudeyras |
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13.45-14.00 | Total syntheses of Pseudoceramines A-D and Spermatinamine Mikael Hillgren |
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14.00-14.15 | Coxsackievirus A24 and cellular receptors on human ocular cells Nitesh Mistry |
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14.15-14.30 | How predicting disorder in proteins help us understand disease Lixiao Wang |
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14.30-14.45 | YscU and its role in Type-III-Secretion Stefan Frost |
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14.45-15.00 | Antibacterial properties of gallium Olena Rzhepishevska |
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15.00-15.30 | Coffee break |
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Session II: Chairpersons Sophie Coudeyras and Mikael Hillgren |
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15.30-15.45 |
Heat temperature requirement A (HtrA) is a Highly Conserved Serine Protease, required for Streptococcus pneumoniae survival in contact with human innate immune system Vladimir Vimberg |
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15.45-16.00 |
Curli fiber assembly in the presence of small peptidomimetic molecules Emma Andersson |
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16.00-16.15 |
Structural and functional characterization of SfaX, protein involved in the regulation of adhesion and motility genes in extraintestinal pathogenic Escherichia coli Patricia Paracuellos |
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16.15-16.30 |
Phagocyte response in fungal infections Marc Röhm |
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16.30-16.45 | Inhibitors of acetylcholinesterase: kinetic studies, crystallography and computation to elucidate the nature of protein-ligand interactions David Andersson |