Publications 2007

Andersson, H., Almqvist, F., and Olsson, R. (2007). Synthesis of 2-substituted pyridines via a regiospecific alkylation, alkynylation, and arylation of pyridine N-oxides. Org Lett 9, 1335-1337.

Andersson, M., Nordstrand, A., Shamaei-Tousi, A., Jansson, A., Bergström, S., and Guo, B. (2007). In situ immune response in brain and kidney during early relapsing fever borreliosis. J Neuroimmunol 183, 26-32.

Bailey, L., Gylfe, A., Sundin, C., Muschiol, S., Elofsson, M., Nordström, P., Henriques-Normark, B., Lugert, R., Waldenström, A., Wolf-Watz, H., et al. (2007). Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle. FEBS Lett 581, 587-595.

Bröms, J., Francis, M., and Forsberg, A. (2007). Diminished LcrV secretion attenuates Yersinia pseudotuberculosis virulence. J Bacteriol 189, 8417-8429.

Carlsson, K., Liu, J., Edqvist, P., and Francis, M. (2007). Extracytoplasmic-stress-responsive pathways modulate type III secretion in Yersinia pseudotuberculosis. Infect Immun 75, 3913-3924.

Carlsson, K., Liu, J., Edqvist, P., and Francis, M. (2007). Influence of the Cpx extracytoplasmic-stress-responsive pathway on Yersinia sp.-eukaryotic cell contact. Infect Immun 75, 4386-4399.

Chorell, E., Das, P., and Almqvist, F. (2007). Diverse functionalization of thiazolo ring-fused 2-pyridones. J Org Chem 72, 4917-4924.

Croxatto, A., Lauritz, J., Chen, C., and Milton, D. (2007). Vibrio anguillarum colonization of rainbow trout integument requires a DNA locus involved in exopolysaccharide transport and biosynthesis. Environ Microbiol 9, 370-382.

Dahlgren, M., Kauppi, A., Olsson, I., Linusson, A., and Elofsson, M. (2007). Design, synthesis, and multivariate quantitative structure-activity relationship of salicylanilides--potent inhibitors of type III secretion in Yersinia. J Med Chem 50, 6177-6188.

Edqvist, P., Aili, M., Liu, J., and Francis, M. (2007). Minimal YopB and YopD translocator secretion by Yersinia is sufficient for Yop-effector delivery into target cells. Microbes Infect 9, 224-233.

Fijolek, A., Hofer, A., and Thelander, L. (2007). Expression, purification, characterization, and in vivo targeting of trypanosome CTP synthetase for treatment of African sleeping sickness. J Biol Chem 282, 11858-11865.

Forsberg, A., and Guina, T. (2007). Type II secretion and type IV pili of Francisella. Ann N Y Acad Sci 1105, 187-201.

Garbom, S., Olofsson, M., Björnfot, A., Srivastava, M., Robinson, V., Oyston, P., Titball, R., and Wolf-Watz, H. (2007). Phenotypic characterization of a virulence-associated protein, VagH, of Yersinia pseudotuberculosis reveals a tight link between VagH and the type III secretion system. Microbiology 153, 1464-1473.

Hainzl, T., Huang, S., and Sauer-Eriksson, A. (2007). Interaction of signal-recognition particle 54 GTPase domain and signal-recognition particle RNA in the free signal-recognition particle. Proc Natl Acad Sci U S A 104, 14911-14916

Johansson, C., Jonsson, M., Marttila, M., Persson, D., Fan, X., Skog, J., Frängsmyr, L., Wadell, G., and Arnberg, N. (2007). Adenoviruses use lactoferrin as a bridge for CAR-independent binding to and infection of epithelial cells. J Virol 81, 954-963.

Johansson, S., Nilsson, E., Elofsson, M., Ahlskog, N., Kihlberg, J., and Arnberg, N. (2007). Multivalent sialic acid conjugates inhibit adenovirus type 37 from binding to and infecting human corneal epithelial cells. Antiviral Res 73, 92-100.

Karlsson, A., and Sauer-Eriksson, A. (2007). Heating of proteins as a means of improving crystallization: a successful case study on a highly amyloidogenic triple mutant of human transthyretin. Acta Crystallogr Sect F Struct Biol Cryst Commun 63, 695-700.

Kauppi, A., Andersson, C., Norberg, H., Sundin, C., Linusson, A., and Elofsson, M. (2007). Inhibitors of type III secretion in Yersinia: design, synthesis and multivariate QSAR of 2-arylsulfonylamino-benzanilides. Bioorg Med Chem 15, 6994-7011.

Klein, M., Andersson, M., Axner, O., and Fällman, E. (2007). Dual-trap technique for reduction of low-frequency noise in force measuring optical tweezers. Appl Opt 46, 405-412.

Larsson, C., Comstedt, P., Olsen, B., and Bergström, S. (2007). First record of Lyme disease Borrelia in the Arctic. Vector Borne Zoonotic Dis 7, 453-456.

Lavander, M., Ericsson, S., Bröms, J., and Forsberg, A. (2007). Twin arginine translocation in Yersinia. Adv Exp Med Biol 603, 258-267.

Lindgren, H., Shen, H., Zingmark, C., Golovliov, I., Conlan, W., and Sjöstedt, A. (2007). Resistance of Francisella tularensis strains against reactive nitrogen and oxygen species with special reference to the role of KatG. Infect Immun 75, 1303-1309.

Nordstrand, A., Bunikis, I., Larsson, C., Tsogbe, K., Schwan, T., Nilsson, M., and Bergström, S. (2007). Tickborne relapsing fever diagnosis obscured by malaria, Togo. Emerg Infect Dis 13, 117-123.

Olofsson, A., Borowik, T., Gröbner, G., and Sauer-Eriksson, A. (2007). Negatively charged phospholipid membranes induce amyloid formation of medin via an alpha-helical intermediate. J Mol Biol 374, 186-194.

Ottmann, C., Yasmin, L., Weyand, M., Veesenmeyer, J.L., Diaz, M.H., Palmer, R.H., Francis, M.S., Hauser, A.R., Wittinghofer, A., and Hallberg, B. (2007). Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis. EMBO J 26, 902-913.

Pinne, M., Thein, M., Denker, K., Benz, R., Coburn, J., and Bergström, S. (2007). Elimination of channel-forming activity by insertional inactivation of the p66 gene in Borrelia burgdorferi. FEMS Microbiol Lett 266, 241-249.

Pudelko, M., Kihlberg, J., and Elofsson, M. (2007). Application of gel-phase 19F NMR spectroscopy for optimization of solid-phase synthesis of a hydrophobic peptide from the signal sequence of the mucin MUC1. J Pept Sci 13, 354-361.

Sjöstedt, A. (2007). Tularemia: history, epidemiology, pathogen physiology, and clinical manifestations. Ann N Y Acad Sci 1105, 1-29.

Skog, J., Edlund, K., Bergenheim, A., and Wadell, G. (2007). Adenoviruses 16 and CV23 efficiently transduce human low-passage brain tumor and cancer stem cells. Mol Ther 15, 2140-2145.

Szalewska-Palasz, A., Johansson, L., Bernardo, L., Skärfstad, E., Stec, E., Brännström, K., and Shingler, V. (2007). Properties of RNA polymerase bypass mutants: implications for the role of ppGpp and its co-factor DksA in controlling transcription dependent on sigma54. J Biol Chem 282, 18046-18056.

Wallner, F., Spjut, S., Boström, D., and Elofsson, M. (2007). Synthesis and evaluation of 2-(2-fluoro-4-hydroxymethyl-5-methoxy-phenoxy)acetic acid as a linker in solid-phase synthesis monitored by gel-phase (19)F NMR spectroscopy. Org Biomol Chem 5, 2464-2471.

Östberg, Y., Berg, S., Comstedt, P., Wieslander, A., and Bergström, S. (2007). Functional analysis of a lipid galactosyltransferase synthesizing the major envelope lipid in the Lyme disease spirochete Borrelia burgdorferi. FEMS Microbiol Lett 272, 22-29

Åberg, V., Fällman, E., Axner, O., Uhlin, B., Hultgren, S., and Almqvist, F. (2007). Pilicides regulate pili expression in E. coli without affecting the functional properties of the pilus rod. Mol Biosyst 3, 214-218 (Highlighted in Chemical Biology (2007), 2, B18)

Åberg, V., and Almqvist, F. (2007). Pilicides-small molecules targeting bacterial virulence. Org Biomol Chem 5, 1827-1834.