Publications 2005

Björnham, O., Fällman, E., Axner, O., Ohlsson, J., Nilsson, U.J., Boren, T., and Schedin, S. (2005). Measurements of the binding force between the Helicobacter pylori adhesin BabA and the Lewis b blood group antigen using optical tweezers. J Biomed Opt 10, 44024.

Bröms, J.E., Edqvist, P.J., Carlsson, K.E., Forsberg, A., and Francis, M.S. (2005). Mapping of a YscY binding domain within the LcrH chaperone that is required for regulation of Yersinia type III secretion. J Bacteriol 187, 7738-7752.

Fällman, E., Schedin, S., Jass, J., Uhlin, B.E., and Axner, O. (2005). The unfolding of the P pili quaternary structure by stretching is reversible, not plastic. EMBO Rep 6, 52-56.

Fällman, M., and Gustavsson, A. (2005). Cellular mechanisms of bacterial internalization counteracted by Yersinia. Int Rev Cytol 246, 135-188.

Hainzl, T., Huang, S., and Sauer-Eriksson, A.E. (2005). Structural insights into SRP RNA: an induced fit mechanism for SRP assembly. RNA 11, 1043-1050.

Hedenström, M., Emtenäs, H., Pemberton, N., Åberg, V., Hultgren, S.J., Pinkner, J.S., Tegman, V., Almqvist, F., Sethson, I., and Kihlberg, J. (2005). NMR studies of interactions between periplasmic chaperones from uropathogenic E. coli and pilicides that interfere with chaperone function and pilus assembly. Org Biomol Chem 3, 4193-4200.

Hörnberg, A., Hultdin, U.W., Olofsson, A., and Sauer-Eriksson, A.E. (2005). The effect of iodide and chloride on transthyretin structure and stability. Biochemistry 44, 9290-9299.

Johansson, S.M., Arnberg, N., Elofsson, M., Wadell, G., and Kihlberg, J. (2005). Multivalent HSA conjugates of 3'-sialyllactose are potent inhibitors of adenoviral cell attachment and infection. Chembiochem 6, 358-364.

Karlsson, A., Olofsson, A., Eneqvist, T., and Sauer-Eriksson, A.E. (2005). Cys114-linked dimers of transthyretin are compatible with amyloid formation. Biochemistry 44, 13063-13070.

Larsson, A., Johansson, S.M., Pinkner, J.S., Hultgren, S.J., Almqvist, F., Kihlberg, J., and Linusson, A. (2005). Multivariate design, synthesis, and biological evaluation of peptide inhibitors of FimC/FimH protein-protein interactions in uropathogenic Escherichia coli. J Med Chem 48, 935-945.

Larsson, P., Oyston, P.C., Chain, P., Chu, M.C., Duffield, M., Fuxelius, H.H., Garcia, E., Halltorp, G., Johansson, D., Isherwood, K.E., et al. (2005). The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nat Genet 37, 153-159.

Lindgren, H., Stenman, L., Tarnvik, A., and Sjöstedt, A. (2005). The contribution of reactive nitrogen and oxygen species to the killing of Francisella tularensis LVS by murine macrophages. Microbes Infect 7, 467-475.

Mogemark, L., McGee, K., Yuan, M., Deleuil, F., and Fällman, M. (2005). Disruption of target cell adhesion structures by the Yersinia effector YopH requires interaction with the substrate domain of p130Cas. Eur J Cell Biol 84, 477-489.

Nordfelth, R., Kauppi, A.M., Norberg, H.A., Wolf-Watz, H., and Elofsson, M. (2005). Small-molecule inhibitors specifically targeting type III secretion. Infect Immun 73, 3104-3114.

Olfat, F.O., Zheng, Q., Oleastro, M., Voland, P., Boren, T., Karttunen, R., Engstrand, L., Rad, R., Prinz, C., and Gerhard, M. (2005). Correlation of the Helicobacter pylori adherence factor BabA with duodenal ulcer disease in four European countries. FEMS Immunol Med Microbiol 44, 151-156.

Pemberton, N., Emtenäs, H., Bostrom, D., Domaille, P.J., Greenberg, W.A., Levin, M.D., Zhu, Z., and Almqvist, F. (2005). Cycloaddition of delta2-thiazolines and acyl ketenes under acidic conditions results in bicyclic 1,3-oxazinones and not 6-acylpenams as earlier reported. Org Lett 7, 1019-1021.

Telepnev, M., Golovliov, I., and Sjöstedt, A. (2005). Francisella tularensis LVS initially activates but subsequently down-regulates intracellular signaling and cytokine secretion in mouse monocytic and human peripheral blood mononuclear cells. Microb Pathog 38, 239-247.

Twine, S., Byström, M., Chen, W., Forsman, M., Golovliov, I., Johansson, A., Kelly, J., Lindgren, H., Svensson, K., Zingmark, C., et al. (2005). A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccine. Infect Immun 73, 8345-8352.

Wallner, F.K., Norberg, H.A., Johansson, A.I., Mogemark, M., and Elofsson, M. (2005). Solid-phase synthesis of serine-based glycosphingolipid analogues for preparation of glycoconjugate arrays. Org Biomol Chem 3, 309-315.

Yuan, M., Deleuil, F., and Fallman, M. (2005). Interaction between the Yersinia tyrosine phosphatase YopH and its macrophage substrate, Fyn-binding protein, Fyb. J Mol Microbiol Biotechnol 9, 214-223.

Yuan, M., Mogemark, L., and Fallman, M. (2005). Fyn binding protein, Fyb, interacts with mammalian actin binding protein, mAbp1. FEBS Lett 579, 2339-2347.

Åberg, V., Hedenstrom, M., Pinkner, J.S., Hultgren, S.J., and Almqvist, F. (2005). C-Terminal properties are important for ring-fused 2-pyridones that interfere with the chaperone function in uropathogenic E. coli. Org Biomol Chem 3, 3886-3892.

Åberg, V., Norman, F., Chorell, E., Westermark, A., Olofsson, A., Sauer-Eriksson, A.E., and Almqvist, F. (2005). Microwave-assisted decarboxylation of bicyclic 2-pyridone scaffolds and identification of Abeta-peptide aggregation inhibitors. Org Biomol Chem 3, 2817-2823.