Publications 2013

Almyroudis NG, Grimm MJ, Davidson BA, Roehm M, Urban CF, Segal BH (2013) NETosis and NADPH oxidase: at the intersection of host defense, inflammation, and injury. Frontiers in Immunology 4: 45

Amer AA, Costa TR, Farag SI, Avican U, Forsberg Å, Francis MS (2013) Genetically engineered frameshifted YopN-TyeA chimeras influence type III secretion system function in Yersinia pseudotuberculosis. PLoS One 8: e77767

Andersson CD, Forsgren N, Akfur C, Allgardsson A, Berg L, Engdahl C, Qian WX, Ekstrom F, Linusson A (2013) Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors. J Med Chem 56: 7615-7624

Andersson EK, Bengtsson C, Evans ML, Chorell E, Sellstedt M, Lindgren AEG, Hufnagel DA, Bhattacharya M, Tessier PM, Wittung-Stafshede P, Almqvist F, Chapman MR (2013) Modulation of Curli Assembly and Pellicle Biofilm Formation by Chemical and Protein Chaperones. Chemistry & Biology 20: 1245-1254

Antti H, Fahlgren A, Näsström E, Kouremenos K, Sunden-Cullberg J, Guo Y, Moritz T, Wolf-Watz H, Johansson A, Fällman M (2013) Metabolic Profiling for Detection of Staphylococcus aureus Infection and Antibiotic Resistance. PLoS One 8: e56971

Arnberg N (2013) Adenovirus E3 protein modulates leukocyte functions. Proceedings of the National Academy of Sciences of the United States of America 110: 19976-19977

Artursson E, Andersson PO, Akfur C, Linusson A, Borjegren S, Ekström F (2013) Catalytic-site conformational equilibrium in nerve-agent adducts of acetylcholinesterase: Possible implications for the HI-6 antidote substrate specificity. Biochem Pharmacol 85: 1389-1397

Barcena-Uribarri I, Thein M, Maier E, Bonde M, Bergström S, Benz R (2013) Use of Nonelectrolytes Reveals the Channel Size and Oligomeric Constitution of the Borrelia burgdorferi P66 Porin. Plos One 8: 11

Bengtsson C, Nelander H, Almqvist F (2013) Asymmetric Synthesis of 2,4,5-Trisubstituted (2)-Thiazolines. Chemistry-a European Journal 19: 9916-9922

Bröms JE, Ishikawa T, Wai SN, Sjöstedt A (2013) A functional VipA-VipB interaction is required for the type VI secretion system activity of Vibrio cholerae O1 strain A1552. BMC Microbiol 13: 96

Byström J, Thomson SJ, Johansson J, Edin ML, Zeldin DC, Gilroy DW, Smith AM, Bishop-Bailey D (2013) Inducible CYP2J2 and Its Product 11,12-EET Promotes Bacterial Phagocytosis: A Role for CYP2J2 Deficiency in the Pathogenesis of Crohn's Disease? Plos One 8: e75107

Cava F, Kuru E, Brun YV, de Pedro MA (2013) Modes of cell wall growth differentiation in rod-shaped bacteria. Current Opinion in Microbiology 16: 731-737

Charpentier E, Doudna JA (2013) Biotechnology: Rewriting a genome. Nature 495: 50-51

Chung JCS, Rzhepishevska O, Ramstedt M, Welch M (2013) Type III secretion system expression in oxygen-limited Pseudomonas aeruginosa cultures is stimulated by isocitrate lyase activity. Open Biology 3: 11

Chylinski K, Le Rhun A, Charpentier E (2013) The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems. RNA Biol 10: 726-737

Cortese K, Howes MT, Lundmark R, Tagliatti E, Bagnato P, Petrelli A, Bono M, McMahon HT, Parton RG, Tacchetti C (2013) The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments. Mol Biol Cell 24: 129-144

Costa TRD, Amer AAA, Farag SI, Wolf-Watz H, Fällman M, Fahlgren A, Edgren T, Francis MS (2013) Type III secretion translocon assemblies that attenuate Yersinia virulence. Cellular Microbiology 15: 1088-1110

Desmarais SM, De Pedro MA, Cava F, Huang KC (2013) Peptidoglycan at its peaks: how chromatographic analyses can reveal bacterial cell wall structure and assembly. Molecular Microbiology 89: 1-13

Doerr T, Cava F, Lam H, Davis BM, Waldor MK (2013) Substrate specificity of an elongation-specific peptidoglycan endopeptidase and its implications for cell wall architecture and growth of Vibrio cholerae. Molecular Microbiology 89: 949-962

Duperthuy M, Sjöström AE, Sabharwal D, Damghani F, Uhlin BE, Wai SN (2013) Role of the Vibrio cholerae Matrix Protein Bap1 in Cross-Resistance to Antimicrobial Peptides. Plos Pathogens 9: e1003620

Edwin A, Rompikuntal P, Björn E, Stier G, Wai SN, Sauer-Eriksson AE (2013) Calcium binding by the PKD1 domain regulates interdomain flexibility in Vibrio cholerae metalloprotease PrtV. Febs Open Bio 3: 263-270

Engstrom P, Nguyen BD, Normark J, Nilsson I, Bastidas RJ, Gylfe A, Elofsson M, Fields KA, Valdivia RH, Wolf-Watz H, Bergström S (2013) Mutations in hemG Mediate Resistance to Salicylidene Acylhydrazides, Demonstrating a Novel Link between Protoporphyrinogen Oxidase (HemG) and Chlamydia trachomatis Infectivity. Journal of Bacteriology 195: 4221-4230

Ermert D, Niemiec MJ, Rohm M, Glenthoj A, Borregaard N, Urban CF (2013) Candida albicans escapes from mouse neutrophils. Journal of Leukocyte Biology 94: 223-236

Francis MS (2013) The pathogenic Yersiniae-advances in the understanding of physiology and virulence. Frontiers in Cellular and Infection Microbiology 3: 51

Fuchino K, Bagchi S, Cantlay S, Sandblad L, Wu D, Bergman J, Kamali-Moghaddam M, Flardh K, Ausmees N (2013) Dynamic gradients of an intermediate filament-like cytoskeleton are recruited by a polarity landmark during apical growth. Proceedings of the National Academy of Sciences of the United States of America 110: E1889-E1897

Fuhrmann J, Mierzwa B, Trentini DB, Spiess S, Lehner A, Charpentier E, Clausen T (2013) Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep 3: 1832-1839

Golovliov I, Twine SM, Shen H, Sjöstedt A, Conlan W (2013) A Delta clpB Mutant of Francisella tularensis Subspecies holarctica Strain, FSC200, Is a More Effective Live Vaccine than F. tularensis LVS in a Mouse Respiratory Challenge Model of Tularemia. Plos One 8: e78671

Greber UF, Arnberg N, Wadell G, Benko M, Kremer EJ (2013) Adenoviruses - from pathogens to therapeutics: a report on the 10th International Adenovirus Meeting. Cellular Microbiology 15: 16-23

Grimm MJ, Vethanayagam RR, Almyroudis NG, Dennis CG, Khan AN, D'Auria AC, Singel KL, Davidson BA, Knight PR, Blackwell TS, Hohl TM, Mansour MK, Vyas JM, Rohm M, Urban CF, Kelkka T, Holmdahl R, Segal BH (2013) Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice. J Immunol 190: 4175-4184

Gross J, Passmore I, Chung JS, Rzhepishevska O, Ramstedt M, Welch M (2013) Universal soldier: Pseudomonas aeruginosa — an opportunistic generalist. Front Biol 8: 387-394

Gupta A, Sharma S, Reichenbach P, Marjavaara L, Nilsson AK, Lingner J, Chabes A, Rothstein R, Chang M (2013) Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools. Genetics 193(4):1095-105

Hedberg ME, Israelsson A, Moore ERB, Svensson-Stadler L, Wai SN, Pietz G, Sandström O, Hernell O, Hammarstrom M-L, Hammarstrom S (2013) Prevotella jejuni sp nov., isolated from the small intestine of a child with coeliac disease. International Journal of Systematic and Evolutionary Microbiology 63: 4218-4223

Hernandez J, Johansson A, Stedt J, Bengtsson S, Porczak A, Granholm S, Gonzalez-Acuna D, Olsen B, Bonnedahl J, Drobni M (2013) Characterization and Comparison of Extended-Spectrum beta-Lactamase (ESBL) Resistance Genotypes and Population Structure of Escherichia coli Isolated from Franklin's Gulls (Leucophaeus pipixcan) and Humans in Chile. Plos One ;8(9):e76150

Hoch NC, Chen ESW, Buckland R, Wang SC, Fazio A, Hammet A, Pellicioli A, Chabes A, Tsai MD, Heierhorst J (2013) Molecular Basis of the Essential S Phase Function of the Rad53 Checkpoint Kinase. Molecular and Cellular Biology 33: 3202-3213

Horvath I, Sellstedt M, Weise C, Nordvall LM, Prasad GK, Olofsson A, Larsson G, Almqvist F, Wittung-Stafshede P (2013) Modulation of alpha-synuclein fibrillization by ring-fused 2-pyridones: Templation and inhibition involve oligomers with different structure. Archives of Biochemistry and Biophysics 532: 84-90

Hosseinzadeh A, Urban CF (2013) Novel insight into neutrophil immune responses by dry mass determination of Candida albicans morphotypes. PLoS One 8: e77993

Hussain M, Banchelin TSL, Andersson H, Olsson R, Almqvist F (2013) Enantioselective Synthesis of Substituted Piperidines by Addition of Aryl Grignard Reagents to Pyridine N-Oxides. Organic Letters 15: 54-57

Ito Y, Vela JL, Matsumura F, Hoshino H, Tyznik A, Lee H, Girardi E, Zajonc DM, Liddington R, Kobayashi M, Bao XF, Bugaytsova J, Borén T, Jin RS, Zong YN, Seeberger PH, Nakayama J, Kronenberg M, Fukuda M (2013) Helicobacter pylori Cholesteryl alpha-Glucosides Contribute to Its Pathogenicity and Immune Response by Natural Killer T Cells. Plos One 8: 12

Karlsson E, Svensson K, Lindgren P, Bystrom M, Sjodin A, Forsman M, Johansson A (2013) The phylogeographic pattern of Francisella tularensis in Sweden indicates a Scandinavian origin of Eurosiberian tularaemia. Environmental Microbiology 15: 634-645

Krishnan KS, Bengtsson C, Good JAD, Mirkhanov S, Chorell E, Johansson LBA, Almqvist F (2013) Synthesis of Fluorescent Ring-Fused 2-Pyridone Peptidomimetics. Journal of Organic Chemistry 78: 12207-12213

Lampe EO, Zingmark C, Hemnann L, Brudal E, Rishovd AL, Bröms J, Hagedorn M, Griffiths GW, Sjöstedt A, Winther-Larsen HC (2013) A study of virulence factors in the fish pathogen F. noatunensis ssp noatunensis. Fish Shellfish Immun 34: 1716-1716

Larsson M, Mishra BK, Tysklind M, Linusson A, Andersson PL (2013) On the use of electronic descriptors for QSAR modelling of PCDDs, PCDFs and dioxin-like PCBs() pound. Sar and Qsar in Environmental Research 24: 727-745

Lindgren AEG, Karlberg T, Ekblad T, Spjut S, Thorsell AG, Andersson CD, Nhan TT, Hellsten V, Weigelt J, Linusson A, Schuler H, Elofsson M (2013) Chemical Probes to Study ADP-Ribosylation: Synthesis and Biochemical Evaluation of Inhibitors of the Human ADP-Ribosyltransferase ARTD3/PARP3. J Med Chem 56: 9556-9568

Lindgren AEG, Karlberg T, Thorsell AG, Hesse M, Spjut S, Ekblad T, Andersson CD, Pinto AF, Weigelt J, Hottiger MO, Linusson A, Elofsson M, Schuler H (2013) PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ARTD3/PARP3. Acs Chemical Biology 8: 1698-1703

Lindgren M, Bröms JE, Meyer L, Golovliov I, Sjöstedt A (2013) The Francisella tularensis LVS DeltapdpC mutant exhibits a unique phenotype during intracellular infection. BMC Microbiol 13: 20

Lindgren M, Eneslätt K, Broms JE, Sjöstedt A (2013) Importance of PdpC, IglC, IglI, and IglG for Modulation of a Host Cell Death Pathway Induced by Francisella tularensis. Infection and Immunity 81: 2076-2084

Lundström JO SM, Hesson JC, Blomgren E, Lindström A, Wahlqvist P, Halling A, Hagelin A, Ahlm C, Evander M, Broman T, Forsman M, Persson Vinnersten TZ. (2013) The geographic distribution of mosquito species in Sweden. Journal of the European Mosquito Control Association 31: 21-35

Mahdavi J, Royer P-J, Sjolinder HS, Azimi S, Self T, Stoof J, Wheldon LM, Brannström K, Wilson R, Moreton J, Moir JWB, Sihlbom C, Borén T, Jonsson A-B, Soultanas P, Ala'Aldeen DAA (2013) Pro-inflammatory cytokines can act as intracellular modulators of commensal bacterial virulence. Open Biology 3: 130048

Mellin JR, Tiensuu T, Becavin C, Gouin E, Johansson J, Cossart P (2013) A riboswitch-regulated antisense RNA in Listeria monocytogenes. Proc Natl Acad Sci U S A 110: 13132-13137

Mohamed N, Nilsson E, Johansson P, Klingstrom J, Evander M, Ahlm C, Bucht G (2013) Development and evaluation of a broad reacting SYBR-green based quantitative real-time PCR for the detection of different hantaviruses. J Clin Virol 56: 280-285

Mortezaei N, Singh B, Bullitt E, Uhlin BE, Andersson M (2013) P-fimbriae in the presence of anti-PapA antibodies: new insight of antibodies action against pathogens. Sci Rep 3: 3393

Norregaard K, Andersson M, Sneppen K, Nielsen PE, Brown S, Oddershede LB (2013) DNA supercoiling enhances cooperativity and efficiency of an epigenetic switch. Proceedings of the National Academy of Sciences of the United States of America 110: 17386-17391

Nylander A, Svensater G, Senadheera DB, Cvitkovitch DG, Davies JR, Persson K (2013) Structural and Functional Analysis of the N-terminal Domain of the Streptococcus gordonii Adhesin Sgo0707. Plos One 8: 12

Obi IR, Francis MS (2013) Demarcating SurA Activities Required for Outer Membrane Targeting of Yersinia pseudotuberculosis Adhesins. Infection and Immunity 81: 2296-2308

Palm-Espling ME, Andersson CD, Bjorn E, Linusson A, Wittung-Stafshede P (2013) Determinants for Simultaneous Binding of Copper and Platinum to Human Chaperone Atox1: Hitchhiking not Hijacking. Plos One 8: 12

Parreira P, Magalhaes A, Reis CA, Borén T, Leckband D, Martins MCL (2013) Bioengineered surfaces promote specific protein-glycan mediated binding of the gastric pathogen Helicobacter pylori. Acta Biomaterialia 9: 8885-8893

Poulsen HO, Johansson A, Granholm S, Kahlmeter G, Sundqvist M (2013) High genetic diversity of nitrofurantoin- or mecillinam-resistant Escherichia coli indicates low propensity for clonal spread. Journal of Antimicrobial Chemotherapy 68: 1974-1977

Roehm M, Lindemann E, Hiller E, Ermert D, Lemuth K, Trkulja D, Sogukpinar O, Brunner H, Rupp S, Urban CF, Sohn K (2013) A family of secreted pathogenesis-related proteins in Candida albicans. Molecular Microbiology 87: 132-151

Russell AB, LeRoux M, Hathazi K, Agnello DM, Ishikawa T, Wiggins PA, Wai SN, Mougous JD (2013) Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors. Nature 496: 508-512

Ryden P, Twine S, Shen H, Harris G, Chen W, Sjöstedt A, Conlan W (2013) Correlates of protection following vaccination of mice with gene deletion mutants of Francisella tularensis subspecies tularensis strain, SCHU S4 that elicit varying degrees of immunity to systemic and respiratory challenge with wild-type bacteria. Molecular Immunology 54: 58-67

Rzhepishevska O, Hakobyan S, Ruhal R, Gautrot J, Barbero D, Ramstedt M (2013) The surface charge of anti-bacterial coatings alters motility and biofilm architecture. Biomaterials Science 1: 589-602

Salzer J, Hallmans G, Nystrom M, Stenlund H, Wadell G, Sundström P (2013) Smoking as a risk factor for multiple sclerosis. Multiple Sclerosis Journal 19: 1022-1027

Salzer J, Hallmans G, Nyström M, Stenlund H, Wadell G, Sundström P (2013) Vitamin A and systemic inflammation as protective factors in multiple sclerosis. Multiple Sclerosis Journal 19: 1046-1051

Salzer J, Nystrom M, Hallmans G, Stenlund H, Wadell G, Sundström P (2013) Epstein-Barr virus antibodies and vitamin D in prospective multiple sclerosis biobank samples. Multiple Sclerosis Journal 19: 1587-1591

Sellstedt M, Dang HT, Prasad GK, Sauer U, Almqvist F (2013) Four-Component Assembly of Natural-Product-Like Ring-Fused Isoquinuclidines. European Journal of Organic Chemistry 2013: 7476-7479

Seper A, Hosseinzadeh A, Gorkiewicz G, Lichtenegger S, Roier S, Leitner DR, Rohm M, Grutsch A, Reidl J, Urban CF, Schild S (2013) Vibrio cholerae Evades Neutrophil Extracellular Traps by the Activity of Two Extracellular Nucleases. Plos Pathogens 9: e1003614

Siegrist MS, Whiteside S, Jewett JC, Aditham A, Cava F, Bertozzi CR (2013) D-Amino Acid Chemical Reporters Reveal Peptidoglycan Dynamics of an Intracellular Pathogen. Acs Chemical Biology 8: 500-505

Silander I, Zelan M, Axner O, Arrhen F, Pendrill L, Foltynowicz A (2013) Optical measurement of the gas number density in a Fabry-Perot cavity. Measurement Science and Technology 24: 5

Tan KY, Lin H, Ramstedt M, Watt FM, Huck WTS, Gautrot JE (2013) Decoupling geometrical and chemical cues directing epidermal stem cell fate on polymer brush-based cell micro-patterns. Integr Biol 5: 899-910

Thay B, Wai SN, Oscarsson J (2013) Staphylococcus aureus alpha-Toxin-Dependent Induction of Host Cell Death by Membrane-Derived Vesicles. Plos One 8: e54661

Thorslund SE, Ermert D, Fahlgren A, Erttmann SF, Nilsson K, Hosseinzadeh A, Urban CF, Fällman M (2013) Role of YopK in Yersinia pseudotuberculosis Resistance against Polymorphonuclear Leukocyte Defense. Infection and Immunity 81: 11-22

Tiensuu T, Andersson C, Ryden P, Johansson J (2013) Cycles of light and dark co-ordinate reversible colony differentiation in Listeria monocytogenes. Molecular Microbiology 87: 909-924

Tsaponina O, Chabes A (2013) Pre-activation of the genome integrity checkpoint increases DNA damage tolerance. Nucleic Acids Research 41: 10371-10378

Tukenmez H, Chen C, Tsaponina O, Chabes A, Byström A (2013) Elongator complex enhances Rnr1 induction in response to DNA damage by promoting Ixr1 expression. Yeast 30: 106-106

Upadhyay AS, Vonderstein K, Pichlmair A, Stehling O, Guo J-T, Lill R, Weber F, Överby AK (2013) Viperin vs. tick-borne encephalitis virus: Mechanisms of a potent antiviral protein. Cytokine 63: 305-305

Vonkavaara M, Pavel STI, Holzl K, Nordfelth R, Sjöstedt A, Stoven S (2013) Francisella Is Sensitive to Insect Antimicrobial Peptides. Journal of Innate Immunity 5: 50-59

Wasserstrom S, Grantcharova N, Ubhayasekera W, Ausmees N, Sandblad L, Flardh K (2013) Non-sporulating ftsZ mutants in Streptomyces coelicolor reveal amino acid residues critical for FtsZ polymerization dynamics. Microbiol-Sgm 159: 890-901

Weber E, Finsterbusch K, Lindquist R, Kröger A, Överby A (2013) Type I interferon protects against lethal Langat virus infection. Cytokine 63: 308-308

Williams JS, Smith DJ, Marjavaara L, Lujan SA, Chabes A, Kunkel TA (2013) Topoisomerase 1-Mediated Removal of Ribonucleotides from Nascent Leading-Strand DNA. Molecular Cell 49: 1010-1015

Zakrisson J, Wiklund K, Axner O, Andersson M (2013) The Shaft of the Type 1 Fimbriae Regulates an External Force to Match the FimH Catch Bond. Biophysical Journal 104: 2137-2148

Zetterström CE, Hasselgren J, Salin O, Davis RA, Quinn RJ, Sundin C, Elofsson M (2013) The Resveratrol Tetramer (-)- Hopeaphenol Inhibits Type III Secretion in the Gram-Negative Pathogens Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Plos One 8(12): e81969