Publications 2011

Lenman Annasara, Steffen Müller, Mari Nygren, Lars Frängsmyr, Thilo Stehle, and Niklas Arnberg. Journal of Virology. 2011. 85:13420-13431. Coagulation factor IX mediates serotype-specific binding of species A adenoviruses to host cells".

Nitesh Mistry, Hirotoshi Inoue, Fariba Jamshidi, Rickard Storm, M. Steven Oberste, and Niklas Arnberg. Coxsackievirus A24 variant uses sialic acid-containing O-linked glycoconjugates as cellular receptor on human ocular cells. Journal of Virology. 2011. 85:11283-11290.

Aplander Karolina, Marko Marttila, Sophie Manner, Niklas Arnberg, Olov Sterner, Ulf Ellervik. Molecular wipes: application to epidemic keratoconjuctivitis. Journal of Medicinal Chemistry. 2011. 54:6670-6675.

Spjut Sara, Weixing Qian, Johannes Bauer, Rickard Storm, Lars Frängsmyr, Thilo Stehle, Niklas Arnberg and Mikael Elofsson. A potent trivalent sialic acid inhibitor of adenovirus type 37 infection of human corneal cells. Angewandte Chemie Int Ed. 2011. 50:6519-6521.

Nilsson Emma, Rickard Storm, Johannes Bauer, Susanne Johansson, Aivar Lookene, Jonas Ångström, Mattias Hedenström, Therese L. Eriksson, Lars Frängsmyr, Simon Rinaldi, Hugh J. Willison, Fatima Pedrosa Domellöf, Thilo Stehle and Niklas Arnberg. The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis. Nature Medicine. 2011. 17:105-109.

Chorell, E.; Bengtsson, C.; Sainte-Luce Banchelin, T.; Das, P.; Uvell, H.; Sinha, A. K.; Pinkner, J. S.; Hultgren, S. J.; Almqvist, F.*, Synthesis and application of a bromomethyl substituted scaffold to be used for efficient optimization of antivirulence activity. Eur. J. Med. Chem, 2011, 46, 1103-1116.

Šachl, R.; Rosenbaum, E.; Sellstedt, M.; Almqvist, F.; Johansson, L. B.-Å. 2011, Locations and Reorientations of Polyaromatic 2-Pyridones in Bilayers of Ganglioside GM1. Langmuir, 2011, 27, 1662–1667.

Bengtsson, C.; Almqvist, F.*, A Selective Intramolecular 5-exo-dig or 6-endo-dig Cyclization en Route to New 2-Furanone or 2-Pyrone Containing Tricyclic Scaffolds. J. Org. Chem. 2011, 76, 9817-9825.

Sellstedt, M.; Almqvist, F.*, A three-component reaction forming naphthyridones – synthesis of lophocladine analogues. Org. Lett., 2011, 13, 5278-5281.

Deem, A., Keszthelyi, A., Blackgrove, T., Vayl, A., Coffey, B., Mathur, R., Chabes, A., & Malkova, A. (2011 Epub 15 Feb) Break-induced replication is highly mutagenic. PLoS Biology. 9(2):e1000594.

Rossmann, M.P., Luo, W., Tsaponina, O., Chabes, A., & Stillman, B. (2011 Epub Apr 8) A common telomeric gene silencing assay is affected by nucleotide metabolism. Mol. Cell. 42, 127-136.

Tsaponina, O., Barsoum, E., Åström, S.U., & Chabes, A. (2011 Epub May 5) Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools. PLoS Genetics. 7(5): e1002061.

Stone, J.E., Kumar, D., Stith, C.M., Inase, A., Iwai, S., Chabes, A., Burgers, P.M., & Kunkel, T. (Epub 2011 Aug 15). Lesion bypass by S. cerevisiae Pol zeta alone. DNA repair.

Thorslund S.E., Edgren T., Pettersson J., Nordfelth R., Sellin M.E., Ivanova E., Francis M.S., Isaksson E.L., Wolf-Watz H., Fällman M. (2011) The RACK1 signaling scaffold protein selectively interacts with Yersinia pseudotuberculosis virulence function. PLoS One. 6(2): e16784.

Liu J., Obi I.R., Thanikkal, E.J., Kieselbach, T., Francis M.S. (2011) Phosphorylated CpxR restricts production of the RovA global regulator in Yersinia pseudotuberculosis. PLoS One. 6(8): e23314

Obi I.R., Nordfelth R., Francis M.S. (2011) Varying dependency of periplasmic peptidyl-prolyl cis/trans isomerases in promoting Yersinia pseudotuberculosis stress tolerance and pathogenicity. Biochem. J. 439: 321-332

Amer A.A., Åhlund M.K., Bröms J.E., Forsberg Å., Francis M.S. (2011) Impact of the N-terminal secretory domain on YopD translocator function in Yersinia pseudotuberculosis type III secretion. J. Bacteriol. 193: 6683-6700

S. E. Thorslund, T. Edgren, J. Pettersson, R. Nordfelth, M. E. Sellin, E. Ivanova, M. S. Francis, E. L. Isaksson, H. Wolf-Watz and M. Fallman, The rack1 signaling scaffold protein selectively interacts with yersinia pseudotuberculosis virulence function, PLoS One 6 (2011), no. 2, e16784.

H. Russmann, K. Panthel, B. Kohn, S. Jellbauer, S. E. Winter, S. Garbom, H. Wolf-Watz, S. Hoffmann, S. Grauling-Halama and G. Geginat, Alternative endogenous protein processing via an autophagy-dependent pathway compensates for yersinia-mediated inhibition of endosomal major histocompatibility complex class ii antigen presentation, Infect Immun 78 (2011), no. 12, 5138-5150.

U. Meinzer, F. Barreau, S. Esmiol-Welterlin, C. Jung, C. Villard, T. Leger, S. Ben-Mkaddem, D. Berrebi, M. Dussaillant, Z. Alnabhani, M. Roy, S. Bonacorsi, H. Wolf-Watz, J. Perroy, V. Ollendorff and J. P. Hugot, Yersinia pseudotuberculosis effector yopj subverts the nod2/rick/tak1 pathway and activates caspase-1 to induce intestinal barrier dysfunction, Cell Host Microbe 11 (2011), no. 4, 337-351.

Mansjö M and Johansson J#. The Riboflavin analog Roseoflavin targets an FMN-riboswitch and blocks Listeria monocytogenes growth, but also stimulates virulence gene-expression and infection. RNA Biology, 8:674-680, 2011.

M. Castelain, S. Ehlers, J. Klinth, S. Lindberg, M. Andersson, B. E. Uhlin, and O.Axner, "Fast uncoiling kinetics of F1C pili expressed by uropathogenic Escherichia coli are revealed on a singel pilus level using Force-Measuring Optical Tweezers," Euro. Biophys. J. with Biophys. Lett. 40, 305-316 (2011).

P. Kluczynski, S. Lundqvist, J. Westberg, and O. Axner, "Faraday rotation spectrometer with sub-second response time for detection of nitric oxide using a cw DFB quantum cascade laser at 5.33 mu m," Appl. Phys. B 103, 451-459 (2011).

P. Kluczynski, M. Jahjah, L. Nähle, O. Axner, S. Belahsene, M. Fischer, J. Koeth, Y. Rouillard, J. Westberg, A. Vicet, and S. LundqvistS, "Detection of acetylene impurities in ethylene and polyethylene manufacturing processes using tunable diode laser spectroscopy in the 3 μm range," Applied Physics B 105, 427-434 (2011).

A. Foltynowicz, I. Silander, and O. Axner, "Reduction of background signals from fiber-based NICE-OHMS," J. Opt. Soc. Am. B 28, 2797-2805 (2011).

J. Westberg, P. Kluczynski, S. Lundqvist, and O. Axner, "Analytical expression for the nth Fourier coefficient of a modulated Lorentzian dispersion lineshape function," J. Quant. Spectrosc. Radiat. Tr 112, 1443-1449 (2011).

L. Lathdavong, J. Shao, P. Kluczynski, S. Lundqvist, and O. Axner, "Methodology for detection of carbon monoxide in hot, humid media by telecommunication distributed feedback laser-based tunable diode laser absorption spectrometry," Appl. Opt. 50, 2531-2550 (2011).

J. Y. Wang, P. Ehlers, I. Silander, and O. Axner, "Dicke narrowing in the dispersion mode of detection and in noise-immune cavity-enhanced optical heterodyne molecular spectroscopy - theory and experimental verification," J. Opt. Soc. Am. B 28, 2390-2401 (2011).

Basmarke-Wehelie R, Sjölinder H, Jurkowski W, Elofsson A, Arnqvist A, Engstrand L, Hagner M, Wallin E, Guan N, Kuranasekera H, Aro H, Jonsson AB
The complement regulator CD46 is bactericidal to Helicobacter pylori and blocks urease activity. Gastroenterology (2011) 141:918-28

Ohno T, Vallström A, Rugge M, Ota H, Graham D Y, Arnqvist A* and Yamaoka Y* Effects of BabA expression during H. pylori infection of Mongolian gerbils. Journal of Infectious Diseases (2011) 203: 726-735

Sjövall JC, Fryland L, Nordberg M, Sjögren F, Garpmo U, Jansson C, Carlsson SA, Bergström S, Ernerudh J, Nyman D, Forsberg P, Ekerfelt. Decreased Th1-type inflammatory cytokine expression in the skin is associated with persisting symptoms after treatment of erythema migrans PLoS One 2011 6:e18220.

Bunikis I, Bunikis-Kutschan S, Bonde M and Bergström S. 2011. Multiplex PCR as a tool for validating plasmid content of Borrelia burgdorferi. J. Microbiol. Meth. 86:243-7 doi:10.1016/j.mimet.2011.05.004.

Kumru OS, Bunikis I, Sorokina I Bergström S, and Zückert W. Towards the Specificity and Role of the Borrelia burgdorferi CtpA Protease in Outer Membrane Protein Processing. 2011 193:5759-65. J Bacteriol.

Deltcheva E, Chylinski K, Sharma C, Gonzales K, Chao Y, Pirzada ZA, Eckert M, Vogel J and Charpentier E. 2011. CRISPR RNA maturation by trans-encoded small RNA and host factor RNAse III. Nature (Article) 471(7340):602-607.

Näslund Salomonsson E, Forslund A-L, Forsberg Å. 2011. Type IV pili in Francisella – A virulence trait in an intracellular pathogen. Invited focused review. Front. Microbio.2:29. doi: 10.3389/fmicb.2011.00029.

Egge-Jacobsen W, Salomonsson-Näslund E, Aas, F E, Forslund A-L, Winther-Larsen HC, Maier, J, Macellaro, A, Kuoppa K, Oyston PCF, Titball RW, Thomas RM, Forsberg Å, Prior, JL, and Koomey M. O-linked glycosylation of the PilA pilin-like protein of Francisella tularensis: structural characterization and identification of PglA, the endogenous protein-targeting oligosaccharyltransferase. J. Bacteriol, 2011. 193:5487-97.

Amer AA, Åhlund, MK, Bröms JE, Forsberg, Å and Francis MS. 2011. Impact of the N-terminal secretory domain on YopD translocator function in Yersinia pseudotuberculosis type III secretion. J. Bacteriol, 2011 Sep 30. [Epub ahead of print] PMID:21965570.

Lindgren H, Honn M, Salomonsson E, Kuoppa K, Forsberg A, Sjöstedt A (2011) Iron content differs between Francisella tularensis subspecies tularensis and subspecies holarctica strains and correlates to their susceptibility to H(2)O(2)-induced killing. Infect Immun 79(3): 1218-1224.

Salomonsson EN, Forslund AL, Forsberg Å (2011) Type IV Pili in Francisella - A virulence trait in an intracellular pathogen. Front Microbiol 2: 29.

Huang, S., Hainzl., T., Grundström, C., Forsman, C., Samuelsson, G. & Sauer-Eriksson, A.E. Structural studies of β-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide (2011) PlosOne, 6(12):e28458

Hainzl, T, Huang, S. Meriläinen, G., Brännström, K. & Sauer-Eriksson, A.E. Structural basis of signal-sequence recognition by the signal recognition particle. (2011) Nature Structural and Molecular Biology, 8(3):389-91.

D. Wang, C. E. Zetterström, M. Gabrielsen, K. S. H. Beckham, J. J. Tree, S. E. Macdonald, O. Byron, T. J. Mitchell, D. L. Gally, P. Herzyk, A. Mahajan, H. Uvell, R. Burchmore, B. O. Smith, M. Elofsson, A. J. Roe. Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence blocking compounds. Journal of Biological Chemistry, 34 (2011) 29992-29931.

S. Yin, R. A. Davis, T. Shelper, M. L. Sykes, V. M. Avery, M. Elofsson, C. Sundin, R. J. Quinn Pseudoceramines A−D, antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp. Organic & Biomolecular Chemistry, 9 (2011) 6755-6760.

A. Slepenkin, H. Chu, M. Elofsson, P. Keyser, E. M. Peterson. Protection of mice from a Chlamydia trachomatis vaginal infection using a salicylidene acylhydrazide microbicide. Journal of Infectious Diseases, 204 (2011) 1313-1320.

Bielig H, Rompikuntal PK, Dongre M, Zurek B, Lindmark B, Ramstedt M, Wai SN, Kufer TA. (2011) NOD-Like Receptor Activation by Outer Membrane Vesicles from Vibrio cholerae Non-O1 Non-O139 Strains Is Modulated by the Quorum-Sensing Regulator HapR. Infect Immun. 79(4):1418-27.

Ramstedt M, Nakao R, Wai SN, Uhlin BE, Boily JF. (2011) Monitoring surface chemistry changes in the bacterial cell wall - multivariate analysis of Cryo-X-ray photoelectron spectroscopy data. J Biol Chem. 286(14):12389-96.

Fei YY., Schmidt A., Bylund G., Johansson DX., Henriksson S., Lebrilla C.,
Solnick JV., Borén T.*, Zhu XD. Use of Real-Time, Label-Free Analysis in Revealing Low-Affinity Binding to Blood Group Antigens by Helicobacter pylori. Anal Chem. 2011 Aug 15;83(16):6336-6341

Ishijima N., Suzuki M., Ashida H., Ichikawa Y., Kanegae Y., Saito I., Borén T., Haas R., Sasakawa C., Mimuro H. BabA-mediated Adherence Is a Potentiator of the Helicobacter pylori Type IV Secretion System Activity. J Biol Chem. 2011 Jul 15; 286(28):25256-64. Epub 2011 May 19.

Moore ME., Borén T., Solnick JV. Life at the margins: Modulation of attachment proteins in Helicobacter pylori. Gut Microbes. 2011 Jan-Feb;2(1):42-6.

Akopyan, K, T. Edgren, R. Rosqvist, H. Fahlgren A, Wolf-Watz. and M Fällman. (2011) Translocation of surface localized effectors in type three secretion. Proc Natl Acad Sci U S A. 108:1639-1644.

Olena Rzhepishevska, Barbro Ekstrand-Hammarström, Maximilian Popp, Erik Björn, Anders Bucht, Anders Sjöstedt, Henrik Antti, and Madeleine Ramstedt. (2011). The antibacterial activity of Ga3+ is influenced by ligand complexation as well as the bacterial carbon source. Appl. Environ. Microbiol. 55:5568-5580.

Linda Tancred, Maxim V. Telepnev, Igor Golovliov, Blanka Andersson Henrik Andersson, Helena Lindgren, and Anders Sjöstedt. (2011). Administration of a donor of nitric oxide inhibits mglA expression of intracellular Francisella tularensis and counteracts phagosomal escape and subversion of TNF-α secretion. J. Med. Microbiol. 60:1570-1583.

Fulton KM, Zhao X, Petit MD, Kilmury SL, Wolfraim LA, House RV, Sjöstedt A, Twine SM. (2011). Immunoproteomic analysis of the human antibody response to natural tularemia infection with type A or type B strains or LVS vaccination. Int J Med Microbiol. 301:591-601.

Jeanette E Bröms, Moa Lavander, Lena Meyer, Anders Sjöstedt. (2011). IglG and IglI of Francisella tularensis LVS are important virulence determinants but dispensable for intracellular growth. Infect. Immun. 79:3683-3696.

Kjell Eneslätt, Cecilia Rietz, Patrik Rydén, Svenja Stöven, Robert V. House, Lawrence A. Wolfraim, Arne Tärnvik and Anders Sjöstedt. (2011) Persistence of cell-mediated immunity three decades after vaccination with the live vaccine strain of Francisella tularensis. Eur. J. Immunol. 41:974-80.

Peyman Kelk, Hadi Abd, Rolf Claesson, Gunnar Sandström, Anders Sjöstedt, and Anders Johansson. (2011) Cellular and molecular response of human macrophages exposed to Aggregatibacter actinomycetemcomitans leukotoxin. Cell Death & Disease. 2:e126.

Helena Lindgren, Marie Honn, Emelie Salomonsson, Kerstin Kuoppa, Åke Forsberg, and Anders Sjöstedt. (2011). Iron content differs between Francisella tularensis subspecies tularensis and subspecies holarctica strains and correlates to their susceptibility to H2O2-induced killing. Infect. Immun. 79:1218-1224.

Tina Broman, Johanna Thelaus, Ann-Christin Andersson, Stina Bäckman, Per Wikström, Eva Larsson, Malin Granberg, Linda Karlsson, Erik Bäck, Henrik Eliasson, Roland Mattsson, A. Sjöstedt and Mats Forsman. (2011). Molecular detection of persistent Francisella tularensis subspecies holarctica in natural waters. Int. J. Microbiol. pii: 851946.

Bianchi, M., Niemiec, M.J., Siler, U., Urban, C.F.#, Reichenbach, J.# (2011) Restoration of anti-Aspergillus defense by neutrophil extracellular traps in human chronic granulomatous disease after gene therapy is calprotectin-dependent. J Allergy Clin Immunol 127, 1243-52 e7.

Vethanayagam, R.R., Almyroudis, N.G., Grimm, M.J., Lewandowski, D.C., Pham, C.T., Blackwell, T.S., Petraitiene, R., Petraitis, V., Walsh, T.J., Urban, C.F., Segal, B.H. (2011) Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense. PLoS One 6, e28149.

Castelain M, Ehlers S, Klinth J, Lindberg S, Andersson M, Uhlin BE, Axner O (2011) Fast uncoiling kinetics of F1C pili expressed by uropathogenic Escherichia coil are revealed on a single pilus level using force-measuring optical tweezers. Eur. Biophys. J. 40:305-316.