National and International Seminar Series 2016
Seminar organised by MIMS
Speaker:
Ivo Boneca
Institute Pasteur, Paris, France
Title: The peptidoglycan as a signalling molecule in the host
Host: Felipe Cava
Place: Betula Bldg 6M
Prof. Boneca research aims at studying the role of bacterial peptidoglycan in host-microbe interactions. Using several bacterial models such as Helicobacter pylori, Neisseria meningitidis, Yersinia sp., and Listeria monocytogenes among others, his lab explores the dynamics of peptidoglycan sensing in the host cell during infection and the way pathogens are able to subvert/modulate the host response by modifying their peptidoglycan.
More information:
https://research.pasteur.fr/en/member/ivo-gomperts-boneca/
National and International Seminar Series 2016
Speaker:
Mathias Hornef
Institute for Medical Microbiology, University Hospital, RWTH Aachen, Germany
Title: Ontogeny of the intestinal host-microbial interaction
Contact/host: Andrea Puhar, MolBiol and MIMS
Room: Betula, bldg 6M, NUS
More information:
http://www.ukaachen.de/en/clinics-institutes/institute-of-medical-microbiology/research/hornef-group.html
https://scholar.google.se/scholar?q=mathias+hornef&btnG=&hl=en&as_sdt=0%2C5
http://www.ncbi.nlm.nih.gov/pubmed/?term=mathias+hornef
Department of Medical Biochemistry and Biophysics Seminar Series
Speaker:
Andrea Puhar
Group leader MIMS
Title:
Regulation of extracellular ATP-dependent inflammation in the gut
Host: Anna Arnqvist
Place: Lilla hörsalen, KBC
MIMS Seminar - Department of Molecular Biology
Speaker:
Tanel Tenson
Title:
Transfer routes of antibiotic resistance
Host: Vasili Hauryliuk, MIMS
Place: Major Groove, Bldg 6M, NUS
Antibiotics are some of the most influential innovations of medicine. However, the spread of resistance is a considerable threat that might take us back to the pre-antibiotic era. The problem is perceived as medical, although more than half of the amount of antibiotics produced is consumed in animal husbandry where resistance can also easily emerge.
The resistance can spread through food products, waste water systems, agricultural practices etc. Isolated transfer events have been characterised that outline these transfer routes, but we lack a quantitative knowledge about the extent and importance of the different segments.
Therefore, we have analyzed resistant bacteria critical for medicine in Southern Estonia, with emphasis on the settings around Tartu. The strains were collected from human samples, animal husbandry, ground waters, sewage and characterized by measuring antibiotic sensitivity patterns and whole genome sequencing. The results suggest transfer routes between the different segments under study.