Month Flat Week Day

Friday, May 10, 2019

Nat and Internat Seminar Series - Genetics, transcriptional factors and models in preclinical studies of prostate cancer

Fri. 10 May, 2019 14:00

Note Room Change!

National and International Seminar Series Spring 2019

Speaker:
Lukas Kenner
Ludwig Boltzmann Inst for Cancer Research, Vienna, Austria

Title:
Genetics, transcriptional factors and models in preclinical studies of prostate cancer

Host: Jenny Persson

Room: Major Groove, Bldg 6L, NUS

Coffee/tea/cookies served 30 min before start

Please contact respective host for enquiries to meet with speaker
General questions regarding the seminar series; please contact This email address is being protected from spambots. You need JavaScript enabled to view it. or This email address is being protected from spambots. You need JavaScript enabled to view it.    

Friday, May 17, 2019

Nat and Internat Seminar Series - Targeting CD1d for cancer immunotherapy

Fri. 17 May, 2019 14:00 - 15:00

NOTE ROOM CHANGE!

National and International Seminar Series Spring 2019

Speaker:
Derek Doherty
Trinity College, Dublin, Ireland

Title:
Targeting CD1d for cancer immunotherapy

Host: Johan Normark

Place: Major Groove, Dept of Molecular Biology, bldg 6L NUS

Coffee/tea/cookies served 30 min before start

Please contact respective host for enquiries to meet with speaker
General questions regarding the seminar series; please contact This email address is being protected from spambots. You need JavaScript enabled to view it. or This email address is being protected from spambots. You need JavaScript enabled to view it.    

Friday, May 24, 2019

Nat and Internat Seminar Series -Towards the elusive mechanism of exocytosis: doing structural biology in living cells

Fri. 24 May, 2019 14:00 - 15:00

NOTE ROOM CHANGE!

National and International Seminar Series Spring 2019

Speaker:
Oriol Gallego
Pompeu Fabra, Barcelona, Spain

Title:
Towards the elusive mechanism of exocytosis: doing structural biology in living cells

Host: Franscesca Aguiló

Room: Major Groove, Dept of Molecular Biology, Bldg 6L, NUS

Coffee/tea/cookies served 30 min before start

Please contact respective host for enquiries to meet with speaker
General questions regarding the seminar series; please contact This email address is being protected from spambots. You need JavaScript enabled to view it. or This email address is being protected from spambots. You need JavaScript enabled to view it.    

Tuesday, May 28, 2019

Ribosome assembly defects abrogate initiation factor mediated inspection of start codon

Tue. 28 May, 2019 11:15 - 12:15

Department of Molecular Biology/MIMS
Extra Seminar

Speaker:
Himanshu Sharma
Indian Institute of Technology Guwahati, Assam, India

Title:
Ribosome assembly defects abrogate initiation factor mediated inspection of start codon

Host:
Jonas Barandun, MIMS group leader and SciLifeLab National Fellow, Department of Molecular Biology

Room: Thymine, Dept Molecular Biology, NUS, bldg 6K/L 2 stairs up

Abstract:
Faithful protein synthesis is ensured by extensive quality control checkpoints using components of the translational machinery. However, the implications of defective ribosome assembly on protein synthesis and the associated translation quality control mechanisms in bacteria remain grossly unaddressed. In this study, using E. coli as a model organism we show that premature ribosomes evade scrutiny of cognate start Codon by initiation factors during translation initiation. Resultantly the defective ribosomes make way into the translation cycle with severely compromised decoding and protein synthesis capabilities. The enfeebled binding of premature ribosomes to initiation factors also licenses the rapid conversion of the 30S (pre) initiation complex to 70S initiation complex. Overall, our work highlights that a mass balance deficit between premature ribosomes and initiation factors steers the entry of premature ribosomes into the translation cycle.
(Co-Author: B. Anand)

Wednesday, May 29, 2019

Proteomic and functional analysis of in vitro systems for studies of drug disposition in the human small intestine and liver

Wed. 29 May, 2019 13:30 - 14:30

Department of Molecular Biology/MIMS
Extra Seminar

Magnus Ölander
Department of Pharmacy, Uppsala University
Title:
Proteomic and functional analysis of
in vitro systems for studies of drug disposition in the human small intestine and liver


Place: Thymine, Molecular Biology bldg. 6K/L (2 stairs up)

Host: Barbara Sixt, MIMS group leader,  Dept of Molecular Biology

 

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