Department of Chemistry Seminar
Speaker:
Aymelt Itzen
Professor, Department Chemistry, Group of Proteinchemistry, TU München, Germany
Title:
Molecular mechanisms of the manipulation of small GTPases in the context of bacterial infections
Abstract:
Intracellular signaling processes of eukaryotic cells are strictly coordinated spatially and temporally. Here, G-proteins of the class of small GTPases play a key regulatory role since they function as molecular switches that stimulate or inhibit intracellular signal progression. Due to the central role of small GTPases in the maintenance of cell homeostasis and in the response to changing environmental conditions, these proteins are frequently targeted by bacterial pathogens. Bacteria manipulate the activities of small GTPases in order to manifest an infection. In this talk, I will discuss molecular mechanisms of the manipulation of small GTPases and other essential intracellular proteins in the context of bacterial infection strategies. In particular, I will focus on the consequences of eukaryotic protein modifications (e.g. adenylylation, phosphocholination, proteolysis) caused by bacterial enzymes and will discuss their application potential.
Host: Christian Hedberg, Dept of Chemistry
Place: KBC, Lilla hörsalen, KB3A9
Medical Biochemistry and Biophysics Seminar Series 2016
Speaker:
Roland Benz
Department of Life Sciences and Chemistry, Jacobs-University Bremen, Germany
Title:
Interaction of anthrax and related A-B-type of toxins with eukaryotic target cells and lipid bilayers
Place: Lecture Hall KB3A9, KBC building 3rd floor
Host: Sven Bergström
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Extra Seminar – Department of Molecular Biology, MIMS/UCMR
Speaker:
Roland Benz
Wisdom Professor of Biotechnology, Department of Life Sciences and Chemistry, Jacobs-University Bremen gGmbH
Honorary Doctor at Umeå University
Titel:
What can we learn from electrophysiology on artificial lipid bilayers? Experiments with bacterial porin channels
Host: Sven Bergström
Place: Thymine, Dept of Molecular Biology, Bldg 6K/L