Video-Transfer-Seminar - John Overington: A data mining synthesis approach to the discovery of impersonalised, robust and safe therapies

EMBL Partnership for Molecular Medicine (FIMM - MIMS - NCMM) joint Special Seminar at the Biomedicum in Helsinki.
Video transfer of the talk to Umeå and Oslo simultanously.

John Overington, EMBL Outstation - Hinxton, European Bioinformatics Institute, Cambridge, UK

"A data mining synthesis approach to the discovery of impersonalised, robust and safe therapies"

Abstract:
Adverse Drug Reactions, ADRs, are a major burden on healthcare systems, and arguably, if patients can be stratified, more novel therapies, tolerable in particular genotyped groups could be developed and launched. We have taken a data synthesis approach to explore ADRs and some of the underlying molecular recognition and pharmacokinetic concepts. We then derived a novel drug combination strategy which theoretically can greatly improve the safety of current therapies and also lead to more predictable and consistent patient population response.

Summary for download

Place: Major Groove, Department of Molecular Biology, bldg 6L, University Hospital Area

Organizer in Sweden: Åke Forsberg
Host at FIMM in Finland: Heidi Virtanen