Design, Synthesis & Evaluation of Ring fused 2-Pyridones Directed at Different Medicinal Targets and Diverse Oriented Synthesis (DOS) Towards New Heterocyclic Scaffolds.
A chemical platform with broad applications and flexibility has been rationally designed to interrupt complicated molecular machines important in microbial pathogenesis. The research programme contains a blend of computer-aided design, synthetic organic chemistry, molecular biology and genetics to investigate and disrupt complex biological systems important in disease processes.
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PI: Fredrik Almqvist
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