We invite you to join the following seminar in the scope of the UCMR Distinguished Guests Seminars Series!

Please register here to get access to the seminar: Registration

 

May 9th, 2022, 11:00-12:00   Venue: via Zoom

Vassilis Gorgoulis, National and Kapodistrian University of Athens, Greece
Title of the talk: “Escape from oncogene-induced senescence”
Host PI: Teresa Frisan

Dr. Gorgoulis is currently Professor and Director of the Department of Histology–Embryology, Faculty of Medicine, National Kapodistrian University of Athens, Greece (www.gorgoulis.gr). He is an elected European Molecular Biology Organization (EMBO) member. He received >30 awards and distinctions. Most of his top ranked publications (e.g. in Nature, Cell, Nat Cell Biol, Mol Cell, J Cell Biol) received instant recognition as they were accompanied by corresponding highlights in editorial articles and/or journal covers. He developed a pioneering senescence biomarker (commercially available under the trademark SenTraGor) and provided guidelines to detect senescence that include also the new biomarker (Cell 2019, Nat Protoc 2021).

Dr. Gorgoulis' main research interests include: Mechanisms leading to genomic instability; The role of the DNA damage response (DDR) network as an anti-tumor barrier (eliciting apoptosis or senescence) and mechanisms leading to escape from these barriers; Development of new compounds and methods to detect senescent cells with precision; The role of the replication licensing machinery in cancer progression; Development of machine learning algorithms to predict biological/drug responses. 

Dr. Gorgoulis has special interest in: molecular diagnostics in Pathology, and is the regional coordinator of the European Quality Assessment Scheme for testing KRAS mutations in colorectal cancer, established by the European Society of Pathology. He is also a coordinator of the Greek national: “Emblematic action to handle SARS-CoV-2 infection: Epidemiological study in Greece via extensive testing for viral and antibody detection, sequencing of the virome and genetic analysis of the carriers” (2020-2022) and his lab was appointed by the government as a national reference lab for COVID-19 tests.

Later this spring:

• June

Nadine Cerf-Bensussan, Laboratory of Intestinal Immunity, Université Paris Descartes-Sorbonne, France