Video transfer of the talk to Umeå and Oslo simultanously.
Speaker: John Overington, EMBL Outstation-Hinxton
Title: A data mining synthesis approach to the discovery of impersonalised, robust and safe therapies
31 May 2012, 10:30, Major Groove, bldg 6L Molecular Biology
Speaker:
John Overington
EMBL Outstation - Hinxton,
European Bioinformatics Institute, Cambridge, UK
Title:
A data mining synthesis approach to the discovery of impersonalised, robust and safe therapies
Abstract:
Adverse Drug Reactions, ADRs, are a major burden on healthcare systems, and arguably, if patients can be stratified, more novel therapies, tolerable in particular genotyped groups could be developed and launched. We have taken a data synthesis approach to explore ADRs and some of the underlying molecular recognition and pharmacokinetic concepts. We then derived a novel drug combination strategy which theoretically can greatly improve the safety of current therapies and also lead to more predictable and consistent patient population response.

Organizer in Sweden: Åke Forsberg
Host at FIMM in Finland: Heidi Virtanen
Place:
Major Groove, Department of Molecular Biology, bldg 6L, University Hospital Area