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UID:8df04d30b06712e84f4ab0bf876124a1http://www.ucmr.umu.se
DTSTAMP:20260622T021203Z
CATEGORIES:General
DESCRIPTION:<strong><span style='font-size: x-small\;'>Extra Seminar - </sp
 an><span style='font-size: x-small\;'> associated with The Department of M
 edical Biochemistry and Biophysics' Seminar Series\, spring 2013</span></s
 trong><span style='font-size: x-small\;'><br /></span><br /><span style='f
 ont-size: x-small\;'><strong>Professor David Gally\, </strong>Division of 
 Infection and Immunity\, The Roslin Institute\, University of Edinburgh\, 
 Edinburgh\, Scotland</span><span style='font-size: x-small\;'> <strong><br
  /><br />'New moronic behaviour and Stx appeal'</strong><br /> <br /><stro
 ng>Abstract: </strong></span><br />\n<p style='text-align: justify\;'><spa
 n style='font-size: 8pt\;'>The seminar will introduce the different pathot
 ypes of <em>E. coli</em> and focus on infections associated with Shiga tox
 in (Stx) producing <em>E. coli</em> (STEC). The talk will cover published 
 information on the potential advantages that Stx may provide for <em>E. co
 li</em> colonising the main reservoir host (ruminants) and then will discu
 ss our recent research examining how both protein and sRNA regulators pres
 ent on integrated bacteriophages can alter host strain phenotype or ‘behav
 iour’.  Overall\, the talk covers how the horizontal acquisition of differ
 ent phage-encoded ‘morons’<sup>1</sup> (‘More’ DNA or more ‘ome’) is drivi
 ng the evolution of Stx-encoding <em>E. coli</em> strains in cattle with s
 erious consequences for humans as an incidental host. </span></p>\n<p><spa
 n> </span></p>\n<p><span style='font-size: 8pt\;'><sup><span>1</span></sup
 ><span>Juhala <em>et al</em> (2000) Genomic sequences of bacteriophages HK
 97 and HK022: pervasive genetic mosaicism in the lambdoid bacteriophages. 
 <em>J Mol Biol</em> 299:27-51.</span></span></p>\n<span style='font-size: 
 x-small\;'><br /><strong>Place:</strong> Lilla hörsalen KB3A9\, KBC<br /><
 br /><strong>Host:</strong> Matthew Francis\, Department of Molecular Biol
 ogy  <br /></span>
DTSTART;TZID=Europe/Stockholm:20130528T151500
DTEND;TZID=Europe/Stockholm:20130528T151500
SUMMARY:Seminar - David Gally: New moronic behaviour and Stx appeal
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/165-general/
 315-seminar-david-gally-new-moronic-behaviour-and-stx-appeal.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<strong><span style='font-size: x-small\;'>Ext
 ra Seminar - </span><span style='font-size: x-small\;'> associated with Th
 e Department of Medical Biochemistry and Biophysics' Seminar Series\, spri
 ng 2013</span></strong><span style='font-size: x-small\;'><br /></span><br
  /><span style='font-size: x-small\;'><strong>Professor David Gally\, </st
 rong>Division of Infection and Immunity\, The Roslin Institute\, Universit
 y of Edinburgh\, Edinburgh\, Scotland</span><span style='font-size: x-smal
 l\;'> <strong><br /><br />'New moronic behaviour and Stx appeal'</strong><
 br /> <br /><strong>Abstract: </strong></span><br />\n<p style='text-align
 : justify\;'><span style='font-size: 8pt\;'>The seminar will introduce the
  different pathotypes of <em>E. coli</em> and focus on infections associat
 ed with Shiga toxin (Stx) producing <em>E. coli</em> (STEC). The talk will
  cover published information on the potential advantages that Stx may prov
 ide for <em>E. coli</em> colonising the main reservoir host (ruminants) an
 d then will discuss our recent research examining how both protein and sRN
 A regulators present on integrated bacteriophages can alter host strain ph
 enotype or ‘behaviour’.  Overall\, the talk covers how the horizontal acqu
 isition of different phage-encoded ‘morons’<sup>1</sup> (‘More’ DNA or mor
 e ‘ome’) is driving the evolution of Stx-encoding <em>E. coli</em> strains
  in cattle with serious consequences for humans as an incidental host. </s
 pan></p>\n<p><span> </span></p>\n<p><span style='font-size: 8pt\;'><sup><s
 pan>1</span></sup><span>Juhala <em>et al</em> (2000) Genomic sequences of 
 bacteriophages HK97 and HK022: pervasive genetic mosaicism in the lambdoid
  bacteriophages. <em>J Mol Biol</em> 299:27-51.</span></span></p>\n<span s
 tyle='font-size: x-small\;'><br /><strong>Place:</strong> Lilla hörsalen K
 B3A9\, KBC<br /><br /><strong>Host:</strong> Matthew Francis\, Department 
 of Molecular Biology  <br /></span>
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