National and International Seminar Series 2015
Speaker:
Silvia Nicolis
Department of Biotechnology and Biosciences University of Milano-Biocca, Italy
Title:
The Sox2 transcription factor in brain development and in neural tumors: genome-wide studies in neural stem cells
Contact: Lena Gunhaga, UCMM
Room: Lecture Hall Betula, Bldg 6M
Abstract:
Sox2 is a transcription factor essential for pluripotent stem cells, also active in stem cells of different tissues. Silvia Nicolis' group investigates the role of Sox2 in the development of the nervous system, in particular of the brain, analysing the molecular mechanisms of its action. In parallel, they also study the possible role of Sox2 in brain tumors. One aim of their studies is to better understand, through the functional investigation of Sox2, its role in the hereditary pathology of the nervous system and in brain tumors, with possible implications for therapy.