Department of Chemistry Seminar
Speaker:
Aymelt Itzen
Professor, Department Chemistry, Group of Proteinchemistry, TU München, Germany
Title:
Molecular mechanisms of the manipulation of small GTPases in the context of bacterial infections
Abstract:
Intracellular signaling processes of eukaryotic cells are strictly coordinated spatially and temporally. Here, G-proteins of the class of small GTPases play a key regulatory role since they function as molecular switches that stimulate or inhibit intracellular signal progression. Due to the central role of small GTPases in the maintenance of cell homeostasis and in the response to changing environmental conditions, these proteins are frequently targeted by bacterial pathogens. Bacteria manipulate the activities of small GTPases in order to manifest an infection. In this talk, I will discuss molecular mechanisms of the manipulation of small GTPases and other essential intracellular proteins in the context of bacterial infection strategies. In particular, I will focus on the consequences of eukaryotic protein modifications (e.g. adenylylation, phosphocholination, proteolysis) caused by bacterial enzymes and will discuss their application potential.
Host: Christian Hedberg, Dept of Chemistry
Place: KBC, Lilla hörsalen, KB3A9
Welcome to this extra UCMR – MIMS seminar!
Extra MIMS-UCMR seminar
Title:
"Virulence Strategies of Enterococci"
Speaker:
Dr. Kimberly Kline
Assistant Professor
Singapore Centre on Environmental Life Sciences
Engineering (SCELSE), School of Biological Sciences,
Nanyang Technological University, Singapore
Hosts: Fredrik Almqvist & Jörgen Johansson
Department of Chemistry/Department of Molecular biology
Place: Dept of Molecular Biology, Seminar Room Thymine (2 stairs up)
More information about Dr. Kline:
http://kimberlyklinelab.com/about/index.html
How to find Thymine:
http://www.umu.se/om-universitetet/kartor/?id=480
Department of Chemistry Seminar
Speaker:
Aymelt Itzen
Professor, Department Chemistry, Group of Proteinchemistry, TU München, Germany
Title:
Molecular mechanisms of the manipulation of small GTPases in the context of bacterial infections
Abstract:
Intracellular signaling processes of eukaryotic cells are strictly coordinated spatially and temporally. Here, G-proteins of the class of small GTPases play a key regulatory role since they function as molecular switches that stimulate or inhibit intracellular signal progression. Due to the central role of small GTPases in the maintenance of cell homeostasis and in the response to changing environmental conditions, these proteins are frequently targeted by bacterial pathogens. Bacteria manipulate the activities of small GTPases in order to manifest an infection. In this talk, I will discuss molecular mechanisms of the manipulation of small GTPases and other essential intracellular proteins in the context of bacterial infection strategies. In particular, I will focus on the consequences of eukaryotic protein modifications (e.g. adenylylation, phosphocholination, proteolysis) caused by bacterial enzymes and will discuss their application potential.
Host: Christian Hedberg, Dept of Chemistry
Place: KBC, Lilla hörsalen, KB3A9
Medical Biochemistry and Biophysics Seminar Series 2016
Speaker:
Roland Benz
Department of Life Sciences and Chemistry, Jacobs-University Bremen, Germany
Title:
Interaction of anthrax and related A-B-type of toxins with eukaryotic target cells and lipid bilayers
Place: Lecture Hall KB3A9, KBC building 3rd floor
Host: Sven Bergström
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Extra Seminar – Department of Molecular Biology, MIMS/UCMR
Speaker:
Roland Benz
Wisdom Professor of Biotechnology, Department of Life Sciences and Chemistry, Jacobs-University Bremen gGmbH
Honorary Doctor at Umeå University
Titel:
What can we learn from electrophysiology on artificial lipid bilayers? Experiments with bacterial porin channels
Host: Sven Bergström
Place: Thymine, Dept of Molecular Biology, Bldg 6K/L
The Laboratory for Molecular Infection Medicine Sweden (MIMS) and The National Doctoral Pogramme in Infections and Antibiotics (NDPIA) invite to a series of open lectures which are given in connection to an experimental workshop on "Alternative Infection Models". The lectures are open to all.
WELCOME!
The lectures are given in connection to an experimental workshop on "Alternative Infection Models" funded by the National Doctoral Programme in Infections and Antibiotics (NDPIA) and organized by The Laboratory for Molecular Infection Medicine Sweden (MIMS) at Umeå University 22-25 August, 2016.
22/8 Monday
09.00
Welcome & Introduction: Bernt Eric Uhlin & Anna Holmström
09.10 – 10.00
Jörgen Johansson, MIMS-UCMR & Dept. of Molecular Biology, Umeå University
"Chicken embryos to study Listeria monocytogenes virulence"
13.00 – 15.00
Jonathan Ewbank, Centre d'Immunologie de Marseille-Luminy, Marseille, France
Part 1: “A general introduction to C. elegans”
Part 2: “C. elegans as a model for host-pathogen interactions”
23/8 Tuesday
08.30 – 09.30
Jonas von Hofsten, UCMM, Umeå University
”Fish for science - the zebrafish model system”
10.30 – 12.00
Nelson Gekara, MIMS-UCMR & Dept. of Molecular Biology, Umeå University
“How to model infections in mice”
24/8 Wednesday
08.30 – 09.30
Sun Nyunt Wai, MIMS-UCMR & Dept. of Molecular Biology, Umeå University
“Predator models in studies of Vibrio cholerae”
13.00 -15.00
Mattias Svensson, Department of Medicine, Huddinge, Karolinska Institutet
Part 1: “New developments in in vitro models of multicellular tissue cultures”
Part 2: “Organotypic models of human tissue and their application in biomedical research”
25/8 Thursday
08.30 – 09.15
Mikael Rhen, UCMR & Dept. of Microbiology,
Tumor and Cell Biology (MTC), Karolinska Institutet
“Probabilistic modelling of infection”
11.00 – 11.45
Anna Fahlgren, UCMR & Dept. of Molecular Biology, Umeå University
“In vivo bioluminescent imaging - methods and applications"
Place:
Major Groove, Dept Molecular Biology, Building 6K/L, NUS
Host:
The Laboratory for Molecular Infection Medicine Sweden (MIMS) and The National Doctoral Programme in Infection and Antibiotics (NDPIA)
Bernt Eric Uhlin
Contact:
Anna Holmström, This email address is being protected from spambots. You need JavaScript enabled to view it.
National and International Seminar Series 2016
Seminar
Speaker:
Teresa Frisan
CMB, Karolinska Institute
Title:
Bacterial genotoxins: an interface between infection and cancer biology
Host:
Maria Fällman, Molbiol, MIMS
Place NUS, Biomedicine building 6L, NUS
Department of Molecular Biology - Extra Seminar
Speaker:
Benoit Kornmann
Institute of Biochemistry, Dept of Biology
ETH Zurich, Switzerland
Title:
Interorganelle communication:
new approaches for new questions
Host: Thomas Grundström
Benoit Kornmann's website at the ETH Zürich
Department of Molecular Biology - Extra Seminar
Speaker:
Sebastian Barg
Department of Medical Cell Biology
Uppsala University
Title:
Assembly of the insulin granule exocytosis machinery
Host: Thomas Grundström
Room: Room E04, Building E, Biomedicine building NUS
MIMS/UCMR - Seminar
Department of Molecular Biology /Department of Clinical Microbiology
Speaker:
Eduardo Villablanca
Department of Medicine, Immunology and Allergy Unit
Karolinska Institute, Stockholm
Title:
Intestinal cell homeostasis at the intestinal barrier
Hosts:
Sun Nyunt Wai, MIMS/UCMR/Dept. of Molecular Biology
Mattias Forsell, UCMR/Dept. of Clinical Microbiology
Room:
Lecture room E04, NUS Campus
Link to UmU Campus map
Open lecture, which is part of the "Basic Course in SEM and TEM, 30 August - 1 September 2016.
Title:
New SEM Applications in Umeå
Speaker:
Michael Andersson, ZEISS Sweden
More information about the course
Webpage of the Umeå Core Facility for Electron Microscopy (UCEM)
Open course keynote lecture
Title:
Phase-plate cryo-EM analysis of nucleosomes and DNA at near-atomic resolution
Speaker
Sara Sandin
Assistant Professor Nanyang Technological University (NTU), Singapore
Host: Linda Sandblad
National and International Seminar Series 2016
Speaker
Thomas Kufer
Department of Immunology, University Hohenheim, Stuttgart, Germany
Title:
Novel aspects of the function of non-inflammasome NLRs in immunity
Host: Andrea Puhar, MIMS and Dept of Molecular Biology
Place: Betula, Bldg 6M, NUS
National and International Seminar Series 2016
Speaker:
Gunilla Karlsson Hedestam
Karolinska institutet
Title:
High resolution studies of antigen-specific B cell responses
Host: Mattias Forsell, CliMi
Place: Betula, Building 6M, NUS Campus
MIMS Extra Seminar
Speaker
Jonathan Lynch
Pacific Biosciences Research Center
University of Hawaii, USA
Title:
Exploring the role that Vibrio fischeri outer membrane vesicles play in animal-bacteria symbiosis
Host Felipe Cava MIMS
Room: Old Library, NUS, Bldg 6K/L, Department of Molecular Biology
MIMS/UCMR Extra Seminar at the Department of Molecular Biology
Speaker:
Thomas Marlovits
Centre for Structural Systems Biology, Hamburg, Germany
and Institute of Molecular Biotechnology, Austrian Academy of Sciences (IMBA)
Speaker:
T3SS: Insights from rewiring a molecular machine
Host: Hans Wolf-Watz
Place: Thymine
National and International Seminar Series 2016
Speaker:
Clare Baker
Department of Physiology, Development and Neuroscience,
University of Cambridge, UK
Title:
The development of olfactory ensheathing cells from the neural crest
Host: Sara Wilson, UCMM
Room: Betula, Building 6M, NUS Campus
National and International Seminar Series
Speaker
Mikael Karlsson
Title:
Neutrophils licence iNKT cells to regulate autoreactive B cell responses
Host:
Kristina Lejon
Room: Betula, Bldg 6M, NUS
National and International Seminar Series 2016
Speaker:
Sonja Best
Innate Immunity and Pathogenesis Unit Laboratory of Virology
NIH, Hamilton, MT, USA
Title:
Restriction of flavivirusreplication by TRIM proteins: from rodents to an unexpected function for human TRIM5
Host: Anna Överby
MIMS/UCMR Extra seminar within the Seminar Series at the Department of Medical Biochemistry and Biophysics
Speaker:
Andreas Diepold
University of Oxford
Title:
Inside the machine - studying the Type III Secretion System in live bacteria
Host: Åke Forsberg
Place: Lilla hörsalen KB3A9, KBC building