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DTSTART:20251026T030000
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BEGIN:VEVENT
UID:53905fd1c5f5a31c6f1a15daa5facd2fhttp://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:Department of Medical Biochemistry and Biophysics Seminar Serie
 s fall 2011<br /><br />Ceu Figueiredo\, IPATIMUP and Medical Faculty of Po
 rto\, Portugal<br />'Clinical relevance of Helicobacter pylori genotyping'
 <br /><br />Place: Lilla hörsalen\, KB3A9\, KBC<br /><br /><br />
DTSTART;TZID=Europe/Stockholm:20110927T151500
DTEND;TZID=Europe/Stockholm:20110927T161500
SUMMARY:Seminar - Ceu Figueiredo: Clinical relevance of Helicobacter pylori
  genotyping
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 133-seminar-ceu-figueiredo-clinical-relevance-of-helicobacter-pylori-genot
 yping.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:Department of Medical Biochemistry and Biophys
 ics Seminar Series fall 2011<br /><br />Ceu Figueiredo\, IPATIMUP and Medi
 cal Faculty of Porto\, Portugal<br />'Clinical relevance of Helicobacter p
 ylori genotyping'<br /><br />Place: Lilla hörsalen\, KB3A9\, KBC<br /><br 
 /><br />
END:VEVENT
BEGIN:VEVENT
UID:a57f653a5054ca2dca42f068e9db9520http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:Department of Biochemistry and Biophysics Seminar Series fall 2
 011<br /><br />Mary Cowman<br />Polytechnic Institute of New York Universi
 ty\, Brooklyn\, U.S.A.<br /><br />Title:<br />Macromolecular crowding by H
 yaluronan in the extracellular matrix<br /><br /><br />Place: Lilla hörsal
 en\, KB3A9\, KBC<br /><br />Hosts: Linus Malm/Göran Larsson
DTSTART;TZID=Europe/Stockholm:20110929T151500
DTEND;TZID=Europe/Stockholm:20110929T151500
SUMMARY:Seminar - Mary Cowman: Macromolecular crowding by Hyaluronan in the
  extracellular matrix
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 134-seminar-mary-cowman-macromolecular-crowding-by-hyaluronan-in-the-extra
 cellular-matrix.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:Department of Biochemistry and Biophysics Semi
 nar Series fall 2011<br /><br />Mary Cowman<br />Polytechnic Institute of 
 New York University\, Brooklyn\, U.S.A.<br /><br />Title:<br />Macromolecu
 lar crowding by Hyaluronan in the extracellular matrix<br /><br /><br />Pl
 ace: Lilla hörsalen\, KB3A9\, KBC<br /><br />Hosts: Linus Malm/Göran Larss
 on
END:VEVENT
BEGIN:VEVENT
UID:52d651c2bf20a2abc35e60736eca2dddhttp://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:National and International Seminar Series Fall 2011:<br /><br /
 >Speaker:<br />Michael Williams<br />University of Aberdeen <br /><br />Ti
 tle:<br />Rho-family GTPases in the Drosophila cellular immune reponse<br 
 /><br /><br />Place: Lecture Hall Betula\, Bldg. 6 M\, NUS
DTSTART;TZID=Europe/Stockholm:20110930T150000
DTEND;TZID=Europe/Stockholm:20110930T160000
SUMMARY:Seminar - Michael Williams: Rho-family GTPases in the Drosophila ce
 llular immune reponse
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 118-seminar-michael-williams-rho-family-gtpases-in-the-drosophila-cellular
 -immune-reponse.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:National and International Seminar Series Fall
  2011:<br /><br />Speaker:<br />Michael Williams<br />University of Aberde
 en <br /><br />Title:<br />Rho-family GTPases in the Drosophila cellular i
 mmune reponse<br /><br /><br />Place: Lecture Hall Betula\, Bldg. 6 M\, NU
 S
END:VEVENT
BEGIN:VEVENT
UID:1ed80ce65d2674249a483c665916e060http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:Department of Medical Biochemistry and Biophysics<br />Speaker:
  <br /><strong>Ola Blixt</strong><br /><br />Faculty of Health Science<br 
 />University of Copenhagen Denmark<br /><br />Title: <br />Biomarker disco
 very platforms for glycomics<br /><br />Place: Lilla hörsalen\, KBC
DTSTART;TZID=Europe/Stockholm:20111004T151500
DTEND;TZID=Europe/Stockholm:20111004T161500
SUMMARY:Seminar  - Ola Blixt: Biomarker discovery platforms for glycomics
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 136-seminar-ola-blixt-biomarker-discovery-platforms-for-glycomics.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:Department of Medical Biochemistry and Biophys
 ics<br />Speaker: <br /><strong>Ola Blixt</strong><br /><br />Faculty of H
 ealth Science<br />University of Copenhagen Denmark<br /><br />Title: <br 
 />Biomarker discovery platforms for glycomics<br /><br />Place: Lilla hörs
 alen\, KBC
END:VEVENT
BEGIN:VEVENT
UID:e173f170c115412d57a86b97b916a7e8http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:The 'National and International' Seminar Series\, fall 2011<br 
 /><br />Speaker: Ruth Palmer\, Department of Molecular Biology<br /><br />
 Title: 'Anaplastic Lymphoma Kinase: Signaling in flies and man'<br /><br /
 >Place: Lecture hall\, Betula\, Bldg. 6M<br /><br /><br />
DTSTART;TZID=Europe/Stockholm:20111007T150000
DTEND;TZID=Europe/Stockholm:20111007T160000
SUMMARY:Seminar - Ruth Palmer: Anaplastic Lymphoma Kinase: Signaling in fli
 es and man
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 119-seminar-ruth-palmer-anaplastic-lymphoma-kinase-signaling-in-flies-and-
 man.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:The 'National and International' Seminar Serie
 s\, fall 2011<br /><br />Speaker: Ruth Palmer\, Department of Molecular Bi
 ology<br /><br />Title: 'Anaplastic Lymphoma Kinase: Signaling in flies an
 d man'<br /><br />Place: Lecture hall\, Betula\, Bldg. 6M<br /><br /><br /
 >
END:VEVENT
BEGIN:VEVENT
UID:549fd8914784fdbe2bee98728c8b6365http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:<p>Seminar för all interested people at KBC and UmU:</p>\n<p> <
 /p>\n<p>Speaker:</p>\n<p><strong>Kerstin Lindblad-Toh</strong></p>\n<p>Dir
 ector\, SciLifeLab Uppsala</p>\n<p>Title:</p>\n<p><strong>SciLifeLab Uppsa
 la\, prospect of future platform activities and possible collaborations</s
 trong></p>\n<p><strong><br /></strong></p>\n<p>Place: Stora hörsalen\, KBC
 <strong><br /></strong></p>
DTSTART;TZID=Europe/Stockholm:20111110T110000
DTEND;TZID=Europe/Stockholm:20111110T120000
SUMMARY:Seminar - Kerstin Lindblad-Toh: SciLifeLab Uppsala\, prospect of fu
 ture  platform activities and possible collaborations
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 153-seminar-kerstin-lindblad-toh-scilifelab-uppsala-prospect-of-future-pla
 tform-activities-and-possible-collaborations.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>Seminar för all interested people at KBC an
 d UmU:</p>\n<p> </p>\n<p>Speaker:</p>\n<p><strong>Kerstin Lindblad-Toh</st
 rong></p>\n<p>Director\, SciLifeLab Uppsala</p>\n<p>Title:</p>\n<p><strong
 >SciLifeLab Uppsala\, prospect of future platform activities and possible 
 collaborations</strong></p>\n<p><strong><br /></strong></p>\n<p>Place: Sto
 ra hörsalen\, KBC<strong><br /></strong></p>
END:VEVENT
BEGIN:VEVENT
UID:a99dc2f4c9125e08125270a999b7266fhttp://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:National and International Seminar Series Fall 2011<br />UCMM\,
  Molecular Biology\, Medical Biosciences\, Clinical Microbiology<br /><br 
 />Speaker:<br /><strong>Stefan Marklund</strong><br />Medical Biosciences\
 , Umeå University<br /><br />Title:<br /><strong>Misfolded superoxide dism
 utase and amyotrophic lateral sclerosis</strong><br /><br />Place: Betula 
 Salen Building 6M NUS
DTSTART;TZID=Europe/Stockholm:20111111T150000
DTEND;TZID=Europe/Stockholm:20111111T160000
SUMMARY:Seminar - Stefan Marklund: Misfolded superoxide dismutase and amyot
 rophic lateral sclerosis
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 84-seminar-stefan-marklund-misfolded-superoxide-dismutase-and-amyotrophic-
 lateral-sclerosis.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:National and International Seminar Series Fall
  2011<br />UCMM\, Molecular Biology\, Medical Biosciences\, Clinical Micro
 biology<br /><br />Speaker:<br /><strong>Stefan Marklund</strong><br />Med
 ical Biosciences\, Umeå University<br /><br />Title:<br /><strong>Misfolde
 d superoxide dismutase and amyotrophic lateral sclerosis</strong><br /><br
  />Place: Betula Salen Building 6M NUS
END:VEVENT
BEGIN:VEVENT
UID:9dee68f0e9fee0d141fdbb0cad1a9518http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:The 'National and International' Seminar Series\, fall 2011<br 
 /><br />Speaker: Pål Falnes\, University of Oslo<br /><br />Title: 'Repair
  and modification of nucleic acids by oxygenases from the AlkB family'<br 
 /><br />Place: Lecture hall\, Betula\, Bldg. 6M\, University Hopsital Camp
 us<br />
DTSTART;TZID=Europe/Stockholm:20111118T150000
DTEND;TZID=Europe/Stockholm:20111118T160000
SUMMARY:Seminar - Pål Falnes: Repair and modification of nucleic acids by o
 xygenases from the AlkB family
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 123-seminar-pal-falnes-repair-and-modification-of-nucleic-acids-by-oxygena
 ses-from-the-alkb-family.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:The 'National and International' Seminar Serie
 s\, fall 2011<br /><br />Speaker: Pål Falnes\, University of Oslo<br /><br
  />Title: 'Repair and modification of nucleic acids by oxygenases from the
  AlkB family'<br /><br />Place: Lecture hall\, Betula\, Bldg. 6M\, Univers
 ity Hopsital Campus<br />
END:VEVENT
BEGIN:VEVENT
UID:6eab49505d7efdd670d7c2eb74d4d49ahttp://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:The Biochemistry and Biophysics Seminar Series fall 2011<br /><
 br />Speaker: <br />Victor Muñoz<br />Centro de Investigaciones Biológicas
  (CSIC)\, Madrid\, Spain<br /><br />Title: 'Combining theory and experimen
 t reveals Ssurprinsingly simple universal rules in protein folding'<br /><
 br />Place: Lecture hall 'Lilla hörsalen'\, KB3A9\, KBC-building<br /><br 
 /><br />
DTSTART;TZID=Europe/Stockholm:20111122T151500
DTEND;TZID=Europe/Stockholm:20111122T161500
SUMMARY:Seminar - Victor Muñoz: Combining theory and experiment reveals sur
 prinsingly simple universal rules in protein folding
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 149-seminar-victor-munoz-combining-theory-and-experiment-reveals-surprinsi
 ngly-simple-universal-rules-in-protein-folding.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:The Biochemistry and Biophysics Seminar Series
  fall 2011<br /><br />Speaker: <br />Victor Muñoz<br />Centro de Investiga
 ciones Biológicas (CSIC)\, Madrid\, Spain<br /><br />Title: 'Combining the
 ory and experiment reveals Ssurprinsingly simple universal rules in protei
 n folding'<br /><br />Place: Lecture hall 'Lilla hörsalen'\, KB3A9\, KBC-b
 uilding<br /><br /><br />
END:VEVENT
BEGIN:VEVENT
UID:857c802956655ed6ae0ceed10e4d61fchttp://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:The 'National and International' Seminar Series\, Fall 2011<br 
 /><br />Speaker: Stefan Björklund\, Medical Chemistry and Biophysics\, Ume
 å University<br /><br />Title: 'The function of <em>Arabidopsis thaliana</
 em> Mediator in development\, stress response and light signaling'<br /><b
 r />Place: Lecture hall\, Betula\, Bldg. 6M<br /><br />
DTSTART;TZID=Europe/Stockholm:20111125T150000
DTEND;TZID=Europe/Stockholm:20111125T160000
SUMMARY:Seminar - Stefan Björklund: The function of Arabidopsis thaliana Me
 diator in development\, stress response and light signaling
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 140-seminar-stefan-bjoerklund-the-function-of-arabidopsis-thaliana-mediato
 r-in-development-stress-response-and-light-signaling.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:The 'National and International' Seminar Serie
 s\, Fall 2011<br /><br />Speaker: Stefan Björklund\, Medical Chemistry and
  Biophysics\, Umeå University<br /><br />Title: 'The function of <em>Arabi
 dopsis thaliana</em> Mediator in development\, stress response and light s
 ignaling'<br /><br />Place: Lecture hall\, Betula\, Bldg. 6M<br /><br />
END:VEVENT
BEGIN:VEVENT
UID:46e0da1dd3a10d5c8a3f615d05580182http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:<p>KBC Lecture</p>\n<p>Tage-Erlander Professor 2011</p>\n<p> </
 p>\n<p><strong>Paul Helquist</strong></p>\n<p>Department of Chemistry & Bi
 ochemistry\, University of Notre Dame\, Notre Dame\, Indiana</p>\n<p> </p>
 \n<p>Title:</p>\n<p><strong>From Simple Diene Chemistry to Therapies for R
 are and Neglected Diseases</strong></p>\n<p> </p>\n<p>Abstract</p>\n<p>In 
 a joint set of ventures\, the Wiest and Helquist laboratories at Notre Dam
 e\, specializing in computational chemistry and drug synthesis\, respectiv
 ely\, are supported by various funding mechanisms to reach out to investig
 ators in other fields and at many institutions to form multi-disciplinary 
 collaborative teams for the purpose of drug development. Most often\, the 
 external collaborators are at medical schools or other biomedical institut
 ions and have major strengths in biological or clinical studies but do not
  have the chemistry expertise required for drug development. These collabo
 rators have often identified a potential therapeutic protein target from c
 ellular studies\, or they have conducted compound screenings to identify i
 nitial hits. The next logical steps in these investigations are the design
  of protein binders or hit optimization\, requiring the computational and 
 synthetic chemistry input of our laboratories. The resulting compounds are
  provided back to the external collaborators and other appropriate parties
  for more extensive biological studies. Over the past few years\, these co
 llaborative ties have been established with many investigators at Cornell 
 University Weill College of Medicine\, Tufts University Medical School\, C
 olumbia University College of Physicians and Surgeons\, Washington Univers
 ity School of Medicine\, University of Texas Southwestern Medical Center\,
  Broad Institute\, Dana-Farber Cancer Institute\, Purdue University\, Stat
 e University of New York at Albany\, and Biological Sciences at Notre Dame
 .</p>\n<p>This presentation will place emphasis on the history of our deve
 lopment of synthetic methods for dienes\, especially with colleagues in Sw
 eden\, and the synthesis of target compounds as potential drugs for treati
 ng cancer and a rare\, inherited disease.</p>\n<p> </p>\n<p><a class='wf_f
 ile' href='images/stories/20111214_Paul_Helquist.pdf' target='_blank'></a>
 <a class='jce_file_custom' href='images/stories/documents/20111214_Paul_He
 lquist.pdf' target='_blank'><span class='wf_file_text'>Abstract with refer
 ences for download here</span></a></p>\n<p><a href='http://vr.se/forskning
 sfinansiering/bidragsbeslut/naturvetenskapochteknikvetenskap/tageerlanders
 gastprofessur/2011paulhelquist.4.122a0d251301f4f334580001738.html' target=
 '_blank'>More information about the Tage Erlander professor 2011</a></p>
DTSTART;TZID=Europe/Stockholm:20111214T130000
DTEND;TZID=Europe/Stockholm:20111214T140000
SUMMARY:KBC Lecture - Paul Helquist: From Simple Diene Chemistry to Therapi
 es for Rare and Neglected Diseases
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 152-kbc-lecture-paul-helquist-from-simple-diene-chemistry-to-therapies-for
 -rare-and-neglected-diseases.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>KBC Lecture</p>\n<p>Tage-Erlander Professor
  2011</p>\n<p> </p>\n<p><strong>Paul Helquist</strong></p>\n<p>Department 
 of Chemistry & Biochemistry\, University of Notre Dame\, Notre Dame\, Indi
 ana</p>\n<p> </p>\n<p>Title:</p>\n<p><strong>From Simple Diene Chemistry t
 o Therapies for Rare and Neglected Diseases</strong></p>\n<p> </p>\n<p>Abs
 tract</p>\n<p>In a joint set of ventures\, the Wiest and Helquist laborato
 ries at Notre Dame\, specializing in computational chemistry and drug synt
 hesis\, respectively\, are supported by various funding mechanisms to reac
 h out to investigators in other fields and at many institutions to form mu
 lti-disciplinary collaborative teams for the purpose of drug development. 
 Most often\, the external collaborators are at medical schools or other bi
 omedical institutions and have major strengths in biological or clinical s
 tudies but do not have the chemistry expertise required for drug developme
 nt. These collaborators have often identified a potential therapeutic prot
 ein target from cellular studies\, or they have conducted compound screeni
 ngs to identify initial hits. The next logical steps in these investigatio
 ns are the design of protein binders or hit optimization\, requiring the c
 omputational and synthetic chemistry input of our laboratories. The result
 ing compounds are provided back to the external collaborators and other ap
 propriate parties for more extensive biological studies. Over the past few
  years\, these collaborative ties have been established with many investig
 ators at Cornell University Weill College of Medicine\, Tufts University M
 edical School\, Columbia University College of Physicians and Surgeons\, W
 ashington University School of Medicine\, University of Texas Southwestern
  Medical Center\, Broad Institute\, Dana-Farber Cancer Institute\, Purdue 
 University\, State University of New York at Albany\, and Biological Scien
 ces at Notre Dame.</p>\n<p>This presentation will place emphasis on the hi
 story of our development of synthetic methods for dienes\, especially with
  colleagues in Sweden\, and the synthesis of target compounds as potential
  drugs for treating cancer and a rare\, inherited disease.</p>\n<p> </p>\n
 <p><a class='wf_file' href='images/stories/20111214_Paul_Helquist.pdf' tar
 get='_blank'></a><a class='jce_file_custom' href='images/stories/documents
 /20111214_Paul_Helquist.pdf' target='_blank'><span class='wf_file_text'>Ab
 stract with references for download here</span></a></p>\n<p><a href='http:
 //vr.se/forskningsfinansiering/bidragsbeslut/naturvetenskapochteknikvetens
 kap/tageerlandersgastprofessur/2011paulhelquist.4.122a0d251301f4f334580001
 738.html' target='_blank'>More information about the Tage Erlander profess
 or 2011</a></p>
END:VEVENT
BEGIN:VEVENT
UID:aa7e0f6e0cec59f4edf93a20e2ef56dbhttp://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:Department of Clinical Microbiology<br /><br />Extra Seminar<br
  />Title:<br />Resolving the stage-specific contribution of the anti-apopt
 otic proteins to humoral immunity<br /><br />Ingela Vikström<br /><br />Wa
 lter and Eliza Hall Institute<br />Melbourne\, Australia<br /><br />Place:
  Betula\, University Hospital\, building 6 M<br /><br />-----------<br /><
 br />Dr Ingela Vikström completed her PhD at the Dept. Med Biosciences\, U
 meå University in 2006. She then relocated to Melbourne Australia were she
  is currently a post doctoral fellow at the Walter and Eliza Hall Institut
 e. Some of her recent publications include:<br /><br />Vikstrom I\, Tarlin
 ton DM. B cell memory and the role of apoptosis in its formation. Mol Immu
 nol. 2011 48:1301-6. <br />Vikstrom I\, Carotta S\, Lüthje K\, Peperzak V\
 , Jost PJ\, Glaser S\, Busslinger M\, Bouillet P\, Strasser A\, Nutt SL\, 
 Tarlinton DM. Mcl-1 is essential for germinal center formation and B cell 
 memory. Science. 2010 330:1095-9<br />Carrington EM\, Vikstrom IB\, Light 
 A\, Sutherland RM\, Londrigan SL\, Mason KD\, Huang DC\, Lew AM\, Tarlinto
 n DM. BH3 mimetics antagonizing restricted prosurvival  Bcl-2 proteins rep
 resent another class of selective immune modulatory drugs. Proc Natl Acad 
 Sci U S A. 2010 107:10967-71.<br /><br /><br /><br />
DTSTART;TZID=Europe/Stockholm:20111221T140000
DTEND;TZID=Europe/Stockholm:20111221T150000
SUMMARY:Seminar - Ingela Vikström: Resolving the stage-specific contributio
 n of the anti-apoptotic proteins to humoral immunity
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 155-seminar-ingela-vikstroem-resolving-the-stage-specific-contribution-of-
 the-anti-apoptotic-proteins-to-humoral-immunity.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:Department of Clinical Microbiology<br /><br /
 >Extra Seminar<br />Title:<br />Resolving the stage-specific contribution 
 of the anti-apoptotic proteins to humoral immunity<br /><br />Ingela Vikst
 röm<br /><br />Walter and Eliza Hall Institute<br />Melbourne\, Australia<
 br /><br />Place: Betula\, University Hospital\, building 6 M<br /><br />-
 ----------<br /><br />Dr Ingela Vikström completed her PhD at the Dept. Me
 d Biosciences\, Umeå University in 2006. She then relocated to Melbourne A
 ustralia were she is currently a post doctoral fellow at the Walter and El
 iza Hall Institute. Some of her recent publications include:<br /><br />Vi
 kstrom I\, Tarlinton DM. B cell memory and the role of apoptosis in its fo
 rmation. Mol Immunol. 2011 48:1301-6. <br />Vikstrom I\, Carotta S\, Lüthj
 e K\, Peperzak V\, Jost PJ\, Glaser S\, Busslinger M\, Bouillet P\, Strass
 er A\, Nutt SL\, Tarlinton DM. Mcl-1 is essential for germinal center form
 ation and B cell memory. Science. 2010 330:1095-9<br />Carrington EM\, Vik
 strom IB\, Light A\, Sutherland RM\, Londrigan SL\, Mason KD\, Huang DC\, 
 Lew AM\, Tarlinton DM. BH3 mimetics antagonizing restricted prosurvival  B
 cl-2 proteins represent another class of selective immune modulatory drugs
 . Proc Natl Acad Sci U S A. 2010 107:10967-71.<br /><br /><br /><br />
END:VEVENT
BEGIN:VEVENT
UID:9f3e4d7f1163f9514468536793ef5202http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:<p>Department of Clinical Microbiology<br /> Extra Seminar <br 
 />Title: <br /><strong>High-Throughput Screening in an Academic Setting\, 
 a Bona Fide Path to Novel Therapeutics and Tool Molecules? </strong></p>\n
 <p>Speaker:<br /><strong>Kurt Lackovic </strong><br /><br />Walter and Eli
 za Hall Institute Melbourne\, Australia <br /><strong>Place: Betula\, Univ
 ersity Hospital\, building 6 M</strong><br /> <br /><br />The Walter and E
 liza Hall Institute of Medical Research was one of the first academic inst
 itutions in the world to establish a high-throughput screening facility. H
 ow this Facility operates\, along with the format of projects\, outcomes t
 o date\, examples of projects\, and recent expansion to include high-conte
 nt screening will be discussed.</p>\n<p> </p>\n<p>Biography Paragraph:</p>
 \n<p>Dr Kurt Lackovic completed his PhD in analytical chemistry in 2003. H
 e then relocated to Sweden for his initial post doctoral placement\, at th
 e Department of Medical Biosciences\, Umeå University\, Sweden. Dr Lackovi
 c returned to Melbourne in October 2006\, immediately taking a position in
  the WEHI High-Throughput Chemical Screening (HTCS) Facility. In his curre
 nt role\, Dr Lackovic is responsible for managing collaborative research p
 rojects seeking lead-like molecules across a broad range of target classes
  and disease types\, developing novel techniques\, and reporting findings.
  In addition\, he is responsible for the HTCS Facility's high-content imag
 ing capabilities.</p>\n<p><br /><strong>Recent publications include: </str
 ong> <br />Croker et al. Fas-mediated neutrophil apoptosis is accelerated 
 by Bid\, Bak\, and Bax and inhibited by Bcl-2 and Mcl-1. Proc Natl AcadSci
  U S A. 2011 108:13135-40. <br /> Lackovic K\, Parisot JP\, Sleebs N\, Bae
 ll JB\, Debien L\, Watson KG\, Curtis JM\,Handman E\, Street IP\, Kedziers
 ki L. Inhibitors of Leishmania GDP-mannose pyrophosphorylase identified by
  high-throughput screening of small-molecule chemical library. Antimicrob 
 Agents Chemother. 2010 54:1712-9.</p>
DTSTART;TZID=Europe/Stockholm:20111222T140000
DTEND;TZID=Europe/Stockholm:20111222T150000
SUMMARY:Seminar- Kurt Lackovic: High-Throughput Screening in an Academic Se
 tting\, a Bona Fide Path to Novel Therapeutics and Tool Molecules?
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 157-seminar-kurt-lackovic-high-throughput-screening-in-an-academic-setting
 -a-bona-fide-path-to-novel-therapeutics-and-tool-molecules.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>Department of Clinical Microbiology<br /> E
 xtra Seminar <br />Title: <br /><strong>High-Throughput Screening in an Ac
 ademic Setting\, a Bona Fide Path to Novel Therapeutics and Tool Molecules
 ? </strong></p>\n<p>Speaker:<br /><strong>Kurt Lackovic </strong><br /><br
  />Walter and Eliza Hall Institute Melbourne\, Australia <br /><strong>Pla
 ce: Betula\, University Hospital\, building 6 M</strong><br /> <br /><br /
 >The Walter and Eliza Hall Institute of Medical Research was one of the fi
 rst academic institutions in the world to establish a high-throughput scre
 ening facility. How this Facility operates\, along with the format of proj
 ects\, outcomes to date\, examples of projects\, and recent expansion to i
 nclude high-content screening will be discussed.</p>\n<p> </p>\n<p>Biograp
 hy Paragraph:</p>\n<p>Dr Kurt Lackovic completed his PhD in analytical che
 mistry in 2003. He then relocated to Sweden for his initial post doctoral 
 placement\, at the Department of Medical Biosciences\, Umeå University\, S
 weden. Dr Lackovic returned to Melbourne in October 2006\, immediately tak
 ing a position in the WEHI High-Throughput Chemical Screening (HTCS) Facil
 ity. In his current role\, Dr Lackovic is responsible for managing collabo
 rative research projects seeking lead-like molecules across a broad range 
 of target classes and disease types\, developing novel techniques\, and re
 porting findings. In addition\, he is responsible for the HTCS Facility's 
 high-content imaging capabilities.</p>\n<p><br /><strong>Recent publicatio
 ns include: </strong> <br />Croker et al. Fas-mediated neutrophil apoptosi
 s is accelerated by Bid\, Bak\, and Bax and inhibited by Bcl-2 and Mcl-1. 
 Proc Natl AcadSci U S A. 2011 108:13135-40. <br /> Lackovic K\, Parisot JP
 \, Sleebs N\, Baell JB\, Debien L\, Watson KG\, Curtis JM\,Handman E\, Str
 eet IP\, Kedzierski L. Inhibitors of Leishmania GDP-mannose pyrophosphoryl
 ase identified by high-throughput screening of small-molecule chemical lib
 rary. Antimicrob Agents Chemother. 2010 54:1712-9.</p>
END:VEVENT
BEGIN:VEVENT
UID:66967b99126f1a297f68a1e883a93a8bhttp://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:<p>Department of Chemistry announces:</p>\n<p>Speaker:</p>\n<p>
 Hindrik Mulder\, Professor\, MD <br />Unit of Molecular Metabolism Lund Un
 iversity <br />Diabetes Centre Department of Clinical Sciences <br /><br /
 >Title: <br />Mitochondrial dysfunction in Type 2 Diabetes - a role for TF
 B1M Host: Henrik Antti\, Department of Chemistry</p>\n<p>Place:<br />Biolo
 gihuset BiA 201 (Biology building)</p>
DTSTART;TZID=Europe/Stockholm:20120126T153000
DTEND;TZID=Europe/Stockholm:20120126T163000
SUMMARY:Seminar - Hindrik Mulder:  Mitochondrial dysfunction in Type 2 Diab
 etes - a role for TFB1M
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 165-seminar-hindrik-mulder-mitochondrial-dysfunction-in-type-2-diabetes-a-
 role-for-tfb1m.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>Department of Chemistry announces:</p>\n<p>
 Speaker:</p>\n<p>Hindrik Mulder\, Professor\, MD <br />Unit of Molecular M
 etabolism Lund University <br />Diabetes Centre Department of Clinical Sci
 ences <br /><br />Title: <br />Mitochondrial dysfunction in Type 2 Diabete
 s - a role for TFB1M Host: Henrik Antti\, Department of Chemistry</p>\n<p>
 Place:<br />Biologihuset BiA 201 (Biology building)</p>
END:VEVENT
BEGIN:VEVENT
UID:071f5a28a33a79231a4621b8f7d3c546http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:Clinical Microbiology / Virology <br />Extra Seminar<br />Speak
 er:<br /><strong>Urs Greber</strong><br />Institute of Molecular Life Scie
 nces\, University of Zurich\, Switzerland<br /><br />Title: <br />Through 
 the eyes of an adenovirus  -- insights into host trafficking & beyond<br /
 ><br />Place:<br />Lecture hall: Department of Infectious Diseases. Buildi
 ng 24\, University Hospital<br />'Undervisningsnod K0'<br /><br />Host: Ya
 -fang Mei\, Department of Clinical Microbiology/Virology<br />E-mail: <spa
 n id='cloak3a5872ea2ab5b917c604965b22028faf'>This email address is being p
 rotected from spambots. You need JavaScript enabled to view it.</span><scr
 ipt type='text/javascript'>\n				document.getElementById('cloak3a5872ea2ab5b91
 7c604965b22028faf').innerHTML = ''\;\n				var prefix = '&#109\;a' + 'i&#108\;'
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DTSTART;TZID=Europe/Stockholm:20120202T100000
DTEND;TZID=Europe/Stockholm:20120202T110000
SUMMARY:Seminar - Urs Greber: Through the eyes of an adenovirus  -- insight
 s into host trafficking & beyond
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 190-seminar-urs-greber-through-the-eyes-of-an-adenovirus-insights-into-hos
 t-trafficking-beyond.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:Clinical Microbiology / Virology <br />Extra S
 eminar<br />Speaker:<br /><strong>Urs Greber</strong><br />Institute of Mo
 lecular Life Sciences\, University of Zurich\, Switzerland<br /><br />Titl
 e: <br />Through the eyes of an adenovirus  -- insights into host traffick
 ing & beyond<br /><br />Place:<br />Lecture hall: Department of Infectious
  Diseases. Building 24\, University Hospital<br />'Undervisningsnod K0'<br
  /><br />Host: Ya-fang Mei\, Department of Clinical Microbiology/Virology<
 br />E-mail: <span id='cloak3a5872ea2ab5b917c604965b22028faf'>This email a
 ddress is being protected from spambots. You need JavaScript enabled to vi
 ew it.</span><script type='text/javascript'>\n				document.getElementById('clo
 ak3a5872ea2ab5b917c604965b22028faf').innerHTML = ''\;\n				var prefix = '&#109
 \;a' + 'i&#108\;' + '&#116\;o'\;\n				var path = 'hr' + 'ef' + '='\;\n				var addy
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END:VEVENT
BEGIN:VEVENT
UID:678d0784d04be69f74089c610fa95233http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:<p>Department of Clinical Microbiology</p>\n<p>Extra - Seminar<
 /p>\n<p>Speaker:</p>\n<p><strong>Olli Salin</strong><br />Department of Bi
 ological Sciences Åbo Akademi University\, Åbo\, Finland</p>\n<p>Title:<br
  /><strong>Approaches to discover antichlamydial compounds</strong></p>\n<
 p> </p>\n<p>Place: KB3A9 Lilla hörsalen KBC</p>
DTSTART;TZID=Europe/Stockholm:20120208T103000
DTEND;TZID=Europe/Stockholm:20120208T113000
SUMMARY:Seminar . Olli Salin: Approaches to discover antichlamydial compoun
 ds
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 185-seminar-olli-salin-approaches-to-discover-antichlamydial-compounds.htm
 l
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>Department of Clinical Microbiology</p>\n<p
 >Extra - Seminar</p>\n<p>Speaker:</p>\n<p><strong>Olli Salin</strong><br /
 >Department of Biological Sciences Åbo Akademi University\, Åbo\, Finland<
 /p>\n<p>Title:<br /><strong>Approaches to discover antichlamydial compound
 s</strong></p>\n<p> </p>\n<p>Place: KB3A9 Lilla hörsalen KBC</p>
END:VEVENT
BEGIN:VEVENT
UID:37f8234087a68734dd90c201bdacf40fhttp://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:<strong>Medical Biochemistry and Biophysics Seminar Series\, sp
 ring 2012</strong><br /><br /><strong>Anders Nordström</strong>\, Departme
 nt of Molecular Biology\, Umeå University<br /><br /><strong>Title:</stron
 g> Quantitative and Kinetic Metabolomics to study mechanisms of drug resis
 tance<br /><br /><strong>Place:</strong> KB3A9\, Lilla hörsalen\, KBC<br /
 ><br /><strong>Host:</strong> Richard Lundmark
DTSTART;TZID=Europe/Stockholm:20120214T151500
DTEND;TZID=Europe/Stockholm:20120214T151500
SUMMARY:Seminar - Anders Nordström: Quantitative and Kinetic Metabolomics t
 o study mechanisms of drug resistance
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 186-seminar-anders-nordstroem-quantitative-and-kinetic-metabolomics-to-stu
 dy-mechanisms-of-drug-resistance.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<strong>Medical Biochemistry and Biophysics Se
 minar Series\, spring 2012</strong><br /><br /><strong>Anders Nordström</s
 trong>\, Department of Molecular Biology\, Umeå University<br /><br /><str
 ong>Title:</strong> Quantitative and Kinetic Metabolomics to study mechani
 sms of drug resistance<br /><br /><strong>Place:</strong> KB3A9\, Lilla hö
 rsalen\, KBC<br /><br /><strong>Host:</strong> Richard Lundmark
END:VEVENT
BEGIN:VEVENT
UID:981a470f052075fae8f01480399b43adhttp://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:Clinical Microbiology / Virology <br />Extra Seminar<br />Speak
 er:<br /><strong>Urs Greber</strong><br />Institute of Molecular Life Scie
 nces\, University of Zurich\, Switzerland<br /><br />Title: <br />Through 
 the eyes of an adenovirus  -- insights into host trafficking & beyond<br /
 ><br />Place:<br />Lecture hall: Department of Infectious Diseases. Buildi
 ng 24\, University Hospital<br />'Undervisningsnod K0'<br /><br />Host: Ya
 -fang Mei\, Department of Clinical Microbiology/Virology<br />E-mail: <spa
 n id='cloak617efbd325f34b550a898b07aa969448'>This email address is being p
 rotected from spambots. You need JavaScript enabled to view it.</span><scr
 ipt type='text/javascript'>\n				document.getElementById('cloak617efbd325f34b5
 50a898b07aa969448').innerHTML = ''\;\n				var prefix = '&#109\;a' + 'i&#108\;'
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 7efbd325f34b550a898b07aa969448 + '\'>'+addy_text617efbd325f34b550a898b07aa
 969448+'<\/a>'\;\n		</script>
DTSTART;TZID=Europe/Stockholm:20120302T100000
DTEND;TZID=Europe/Stockholm:20120302T110000
SUMMARY:Seminar - Urs Greber: Through the eyes of an adenovirus  -- insight
 s into host trafficking & beyond
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 191-seminar-urs-greber-through-the-eyes-of-an-adenovirus-insights-into-hos
 t-trafficking-beyond.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:Clinical Microbiology / Virology <br />Extra S
 eminar<br />Speaker:<br /><strong>Urs Greber</strong><br />Institute of Mo
 lecular Life Sciences\, University of Zurich\, Switzerland<br /><br />Titl
 e: <br />Through the eyes of an adenovirus  -- insights into host traffick
 ing & beyond<br /><br />Place:<br />Lecture hall: Department of Infectious
  Diseases. Building 24\, University Hospital<br />'Undervisningsnod K0'<br
  /><br />Host: Ya-fang Mei\, Department of Clinical Microbiology/Virology<
 br />E-mail: <span id='cloak617efbd325f34b550a898b07aa969448'>This email a
 ddress is being protected from spambots. You need JavaScript enabled to vi
 ew it.</span><script type='text/javascript'>\n				document.getElementById('clo
 ak617efbd325f34b550a898b07aa969448').innerHTML = ''\;\n				var prefix = '&#109
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END:VEVENT
BEGIN:VEVENT
UID:5018be7860acbd0610f3b451a383a1f9http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:<p>Joint seminar UCMM - UCMR- MIMS - KBC</p>\n<p>Speaker:</p>\n
 <p><strong>Myles Axton</strong><br />Editor\, Nature Genetics</p>\n<p><br 
 />Title:</p>\n<p><strong>Publishing your work in Nature journals</strong><
 /p>\n<p> </p>\n<p>Host:</p>\n<p>Helena Edlund</p>\n<p> </p>\n<p>Place: Sto
 ra Hörsalen KB3B1\, KBC</p>
DTSTART;TZID=Europe/Stockholm:20120502T140000
DTEND;TZID=Europe/Stockholm:20120502T150000
SUMMARY:Seminar - Myles Axton: Publishing your work in Nature journals
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 195-seminar-myles-axton-publishing-your-work-in-nature-journals.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>Joint seminar UCMM - UCMR- MIMS - KBC</p>\n
 <p>Speaker:</p>\n<p><strong>Myles Axton</strong><br />Editor\, Nature Gene
 tics</p>\n<p><br />Title:</p>\n<p><strong>Publishing your work in Nature j
 ournals</strong></p>\n<p> </p>\n<p>Host:</p>\n<p>Helena Edlund</p>\n<p> </
 p>\n<p>Place: Stora Hörsalen KB3B1\, KBC</p>
END:VEVENT
BEGIN:VEVENT
UID:b19863b60a719aad7fe0a497d688b4f9http://www.ucmr.umu.se
DTSTAMP:20260429T212606Z
CATEGORIES:Seminar
DESCRIPTION:<br /><strong>EMBL Partnership for Molecular Medicine (FIMM - M
 IMS - NCMM) joint Special Seminar at the Biomedicum in Helsinki.</strong><
 br />Video transfer of the talk to Umeå and Oslo simultanously.<br /><br /
 ><strong>John Overington</strong>\, EMBL Outstation - Hinxton\, European B
 ioinformatics Institute\, Cambridge\, UK<br /><br /><strong>'A data mining
  synthesis approach to the discovery of impersonalised\, robust and safe t
 herapies'</strong><br /><br /><strong>Abstract:</strong><br /><span style=
 'font-size: x-small\;'>Adverse Drug Reactions\, ADRs\, are a major burden 
 on healthcare systems\, and arguably\, if patients can be stratified\, mor
 e novel therapies\, tolerable in particular genotyped groups could be deve
 loped and launched. We have taken a data synthesis approach to explore ADR
 s and some of the underlying molecular recognition and pharmacokinetic con
 cepts. We then derived a novel drug combination strategy which theoretical
 ly can greatly improve the safety of current therapies and also lead to mo
 re predictable and consistent patient population response.</span><br /><br
  /><a class='jce_file' href='images/stories/documents/John_Overington_FIMM
 _Special_Seminar_talk_ad.pdf' target='_blank'><img class='jce_icon' src='p
 lugins/editors/jce/tiny_mce/plugins/filemanager/img/ext/pdf_small.gif' sty
 le='border: 0px\; vertical-align: middle\;' alt='pdf' /> Summary for downl
 oad</a><br /><br /><strong>Place:</strong> Major Groove\, Department of Mo
 lecular Biology\, bldg 6L\, University Hospital Area<br /><br /><strong>Or
 ganizer in Sweden:</strong> Åke Forsberg<br /><strong>Host at FIMM in Finl
 and:</strong> Heidi Virtanen<br /><strong></strong>
DTSTART;TZID=Europe/Stockholm:20120531T103000
DTEND;TZID=Europe/Stockholm:20120531T113000
SUMMARY:Video-Transfer-Seminar - John Overington: A data mining synthesis a
 pproach to the discovery of impersonalised\, robust and safe therapies
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 201-video-transfer-seminar-john-overington-a-data-mining-synthesis-approac
 h-to-the-discovery-of-impersonalised-robust-and-safe-therapies.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<br /><strong>EMBL Partnership for Molecular M
 edicine (FIMM - MIMS - NCMM) joint Special Seminar at the Biomedicum in He
 lsinki.</strong><br />Video transfer of the talk to Umeå and Oslo simultan
 ously.<br /><br /><strong>John Overington</strong>\, EMBL Outstation - Hin
 xton\, European Bioinformatics Institute\, Cambridge\, UK<br /><br /><stro
 ng>'A data mining synthesis approach to the discovery of impersonalised\, 
 robust and safe therapies'</strong><br /><br /><strong>Abstract:</strong><
 br /><span style='font-size: x-small\;'>Adverse Drug Reactions\, ADRs\, ar
 e a major burden on healthcare systems\, and arguably\, if patients can be
  stratified\, more novel therapies\, tolerable in particular genotyped gro
 ups could be developed and launched. We have taken a data synthesis approa
 ch to explore ADRs and some of the underlying molecular recognition and ph
 armacokinetic concepts. We then derived a novel drug combination strategy 
 which theoretically can greatly improve the safety of current therapies an
 d also lead to more predictable and consistent patient population response
 .</span><br /><br /><a class='jce_file' href='images/stories/documents/Joh
 n_Overington_FIMM_Special_Seminar_talk_ad.pdf' target='_blank'><img class=
 'jce_icon' src='plugins/editors/jce/tiny_mce/plugins/filemanager/img/ext/p
 df_small.gif' style='border: 0px\; vertical-align: middle\;' alt='pdf' /> 
 Summary for download</a><br /><br /><strong>Place:</strong> Major Groove\,
  Department of Molecular Biology\, bldg 6L\, University Hospital Area<br /
 ><br /><strong>Organizer in Sweden:</strong> Åke Forsberg<br /><strong>Hos
 t at FIMM in Finland:</strong> Heidi Virtanen<br /><strong></strong>
END:VEVENT
END:VCALENDAR
