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DTSTART:20251026T030000
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RDATE:20271031T030000
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DTSTART:20260329T020000
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BEGIN:VEVENT
UID:20140228T140000UTC-bc14f6@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>National and International Seminar Series 2014<br /><br />Sp
 eaker:<br /><strong>Olov Andersson</strong><br />Karolinska Insitute<br />
 <br />Title:&nbsp\;<br /><strong>Drug discovery in zebrafish for pancreati
 c ? -cell regeneration</strong><br />Host: Jonas von Hofsten\, UCMM</p>\n<
 p>Place: Betula salen\, bldg. 6M\, NUS</p>
DTSTART;TZID=Europe/Stockholm:20140228T150000
DTEND;TZID=Europe/Stockholm:20140228T160000
SUMMARY:Nat. and Internat. Seminar Series - Olov Andersson
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 359-nat-and-internat-seminar-series-olov-andersson.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>National and International Seminar Series 2
 014<br /><br />Speaker:<br /><strong>Olov Andersson</strong><br />Karolins
 ka Insitute<br /><br />Title:&nbsp\;<br /><strong>Drug discovery in zebraf
 ish for pancreatic ? -cell regeneration</strong><br />Host: Jonas von Hofs
 ten\, UCMM</p>\n<p>Place: Betula salen\, bldg. 6M\, NUS</p>
END:VEVENT
BEGIN:VEVENT
UID:20140523T120000UTC-556ad0@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>National and International Seminar Series 2014<br /><br />Sp
 eaker:<br /><strong>Frederique Le Roux</strong><br />Station Biologique de
  Roscoff\, France<br /><br />Title:&nbsp\;<br /><strong>Population\, compa
 rative and functional genomics identifies virulence-associated traits in v
 ibrios infected marine invertebrate</strong><br />Host: Marylise Duperthuy
 \, MolBiol</p>\n<p>Place: Betula salen\, bldg. 6M\, NUS</p>
DTSTART;TZID=Europe/Stockholm:20140523T140000
DTEND;TZID=Europe/Stockholm:20140523T150000
SUMMARY:Changed date - Nat. and Internat. Seminar Series - Frederique Le Ro
 ux
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 358-changed-date-nat-and-internat-seminar-series-frederique-le-roux.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>National and International Seminar Series 2
 014<br /><br />Speaker:<br /><strong>Frederique Le Roux</strong><br />Stat
 ion Biologique de Roscoff\, France<br /><br />Title:&nbsp\;<br /><strong>P
 opulation\, comparative and functional genomics identifies virulence-assoc
 iated traits in vibrios infected marine invertebrate</strong><br />Host: M
 arylise Duperthuy\, MolBiol</p>\n<p>Place: Betula salen\, bldg. 6M\, NUS</
 p>
END:VEVENT
BEGIN:VEVENT
UID:20140613T120000UTC-26ea8f@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p><strong>MIMS Special Seminar</strong></p>\n<p>Speaker:&nbsp\
 ;<br /><strong>Prof. Matthew K. Waldor</strong><br />Howard Hughes Medical
  Institute<br />Brigham and Women's Hospital<br />Havard University<br />B
 oston\, MA\, USA</p>\n<p>Title:<br /><strong>Monitoring pathogen populatio
 n dynamics with deep sequencing</strong></p>\n<p>&nbsp\;</p>\n<p>Host: Fel
 ipe Cava\, MIMS<br />Place: Major Groove\, Department of Molecular Biology
 \, building 6K/L\, NUS Campus&nbsp\;</p>\n<p>&nbsp\;</p>\n<p><strong>After
  the seminar\, we welcome postdoc and PhD students to have a fika with Mat
 thew Waldor while they discuss their last results.</strong></p>\n<p><stron
 g>If you are interested\, please send an email to <span id='cloak74a983329
 ae78528569012903d949b1e'>This email address is being protected from spambo
 ts. You need JavaScript enabled to view it.</span><script type='text/javas
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DTSTART;TZID=Europe/Stockholm:20140613T140000
DTEND;TZID=Europe/Stockholm:20140613T150000
SUMMARY:MIMS Special Seminar- Matthew K. Waldor: Monitoring pathogen popula
 tion dynamics with deep sequencing
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 361-mims-special-seminar-matthew-k-waldor-monitoring-pathogen-population-d
 ynamics-with-deep-sequencing.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p><strong>MIMS Special Seminar</strong></p>\n
 <p>Speaker:&nbsp\;<br /><strong>Prof. Matthew K. Waldor</strong><br />Howa
 rd Hughes Medical Institute<br />Brigham and Women's Hospital<br />Havard 
 University<br />Boston\, MA\, USA</p>\n<p>Title:<br /><strong>Monitoring p
 athogen population dynamics with deep sequencing</strong></p>\n<p>&nbsp\;<
 /p>\n<p>Host: Felipe Cava\, MIMS<br />Place: Major Groove\, Department of 
 Molecular Biology\, building 6K/L\, NUS Campus&nbsp\;</p>\n<p>&nbsp\;</p>
 \n<p><strong>After the seminar\, we welcome postdoc and PhD students to ha
 ve a fika with Matthew Waldor while they discuss their last results.</stro
 ng></p>\n<p><strong>If you are interested\, please send an email to <span 
 id='cloak74a983329ae78528569012903d949b1e'>This email address is being pro
 tected from spambots. You need JavaScript enabled to view it.</span><scrip
 t type='text/javascript'>
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END:VEVENT
BEGIN:VEVENT
UID:20140623T120000UTC-b6f0f0@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
CATEGORIES:Events
DESCRIPTION:<p>UCMR Extra seminar<br />Monday\, 23 June 14.00\, at Thymine\
 , bld 6 K/L NUS</p>\n<p>Speaker<br /><strong>Dr. Jordi Torrelles</strong><
 br />The Ohio State University<br />Department of Internal Medicine<br />C
 enter for Microbial Interface Biology</p>\n<p>Title:<br /><strong>'Impact 
 of the human lung mucosa on Mycobacterium tuberculosis pathogenesis'</stro
 ng></p>\n<p>Host:<br />Olena Rzhepishevska\, PhD<br />Department of Chemis
 try<br />Umeå University<br />Tel. 0046722029918</p>\n<p>&nbsp\;</p>\n<p>R
 oom Thymine/Molecular Biology\, NUS area</p>
DTSTART;TZID=Europe/Stockholm:20140623T140000
DTEND;TZID=Europe/Stockholm:20140623T150000
SUMMARY:Seminar - Jordi Torrelles: Impact of the human lung mucosa on Mycob
 acterium tuberculosis pathogenesis
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 363-seminar-jordi-torrelles-impact-of-the-human-lung-mucosa-on-mycobacteri
 um-tuberculosis-pathogenesis.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>UCMR Extra seminar<br />Monday\, 23 June 14
 .00\, at Thymine\, bld 6 K/L NUS</p>\n<p>Speaker<br /><strong>Dr. Jordi To
 rrelles</strong><br />The Ohio State University<br />Department of Interna
 l Medicine<br />Center for Microbial Interface Biology</p>\n<p>Title:<br /
 ><strong>'Impact of the human lung mucosa on Mycobacterium tuberculosis pa
 thogenesis'</strong></p>\n<p>Host:<br />Olena Rzhepishevska\, PhD<br />Dep
 artment of Chemistry<br />Umeå University<br />Tel. 0046722029918</p>\n<p>
 &nbsp\;</p>\n<p>Room Thymine/Molecular Biology\, NUS area</p>
END:VEVENT
BEGIN:VEVENT
UID:20141205T140000UTC-f50915@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>National and International Seminar Series 2014</p>\n<p>Speak
 er:<br /><strong>Lars Bode</strong><br />UCSD\, USA<br /><br />Title: tba<
 br /><br />Room: Betula\, bldg 6M</p>
DTSTART;TZID=Europe/Stockholm:20141005T150000
DTEND;TZID=Europe/Stockholm:20141005T160000
SUMMARY:Nat and Internat Seminar Series - Lars Bode
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 376-nat-and-internat-seminar-series-lars-bode.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>National and International Seminar Series 2
 014</p>\n<p>Speaker:<br /><strong>Lars Bode</strong><br />UCSD\, USA<br />
 <br />Title: tba<br /><br />Room: Betula\, bldg 6M</p>
END:VEVENT
BEGIN:VEVENT
UID:20141021T131500UTC-5bd117@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p><br /><strong>Medical Biochemistry and Biophysics</strong><b
 r />Seminar<br />Speaker:<br /><strong>Lee Makowski</strong><br />Northeas
 tern University\, Boston (MA)\, USA.</p>\n<p>Title:<br /><strong>X-ray sol
 ution scattering characterization of the structural ensemble of adenylate 
 kinase</strong></p>\n<p>Host: Magnus Wolf-Watz</p>\n<p>Room Lilla hörsalen
 \, KB3A9</p>\n<p>—————————</p>
DTSTART;TZID=Europe/Stockholm:20141021T151500
DTEND;TZID=Europe/Stockholm:20141021T161500
SUMMARY:Seminar - Lee Makowski: X-ray solution scattering characterization 
 of the structural ensemble of adenylate kinase
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 372-seminar-lee-makowski-x-ray-solution-scattering-characterization-of-the
 -structural-ensemble-of-adenylate-kinase.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p><br /><strong>Medical Biochemistry and Biop
 hysics</strong><br />Seminar<br />Speaker:<br /><strong>Lee Makowski</stro
 ng><br />Northeastern University\, Boston (MA)\, USA.</p>\n<p>Title:<br />
 <strong>X-ray solution scattering characterization of the structural ensem
 ble of adenylate kinase</strong></p>\n<p>Host: Magnus Wolf-Watz</p>\n<p>Ro
 om Lilla hörsalen\, KB3A9</p>\n<p>—————————</p>
END:VEVENT
BEGIN:VEVENT
UID:20141023T130000UTC-1a6236@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>KBC / UCMR Seminar<br /> <br /> <strong>Adam Olsson</strong>
 <br /> McGill University\, Canada<br /> <br /> Title:<br /> '<strong>Acous
 tic Sensing of Bacterium-Substratum Interfaces</strong>'<br /> <br /> Room
 : KB3B3\, KBC<br /> <br /> Host: Madeleine Ramstedt<br /> <br /> Abstract:
 <br /> Acoustic Sensing of Bacterium-Substratum Interfaces<br /> Adam L.J.
  Olsson<br /> McGill University<br /> &nbsp\;<br /> Bacterial adhesion to 
 surfaces and subsequent biofilm formation is an important phenomenon in ma
 ny areas including\, amongst others\, biomedical engineering\, food proces
 sing and water treatment. &nbsp\;Since biofilms essentially originate from
  only a few initial bacterial colonizers\, understanding the mechanisms go
 verning the initial bacterial adhesion event may help designing surfaces w
 ith the ability to manipulate biofilm formation.<br /> <br /> This present
 ation explores the possibilities to utilize a quartz crystal microbalance 
 with dissipation monitoring (QCM-D) to acoustically sense the mechanical p
 roperties of the bacterium-surface interface. The QCM-D is generally consi
 dered a mass balance\, where a negative shift in the resonance frequency o
 f a quartz crystal sensor is proportional to attached mass. However\, in t
 he case of bacterial adhesion\, the surface attached bacterium possesses a
  resonance frequency that couples to the oscillation of the sensor surface
 . The resulting frequency shift of this “coupled resonance” is either nega
 tive or positive\, depending on the ratio between QCM-D resonance frequenc
 y and the bacterium resonance frequency which\, in turn\, is determined by
  its mass and surface contact stiffness. Thus\, analyzing bacterial adhesi
 on in QCM-D within the context of “coupled resonance” offers a unique oppo
 rtunity to monitor mechanical properties of bacterium-surface contacts.<br
  /> <br /> Since the quartz sensor is mounted in a temperature controlled 
 flow module\, and because change in resonance frequency of the sensor is m
 onitored in real time\, it possible to follow dynamic changes of the bacte
 rium-surface contact during both the initial adhesion event as well as dur
 ing subsequent biofilm growth. Another important aspect of the method is t
 hat the stiffness\, which is related to bond strength\, is investigated wi
 thout detaching the bacteria from the surface\; hence the method is non-de
 structive.<br /> &nbsp\;<br /> &nbsp\;</p>
DTSTART;TZID=Europe/Stockholm:20141023T150000
DTEND;TZID=Europe/Stockholm:20141023T160000
SUMMARY:Seminar- Adam Olsson: Acoustic Sensing of Bacterium-Substratum Inte
 rfaces'
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 369-seminar-adam-olsson-acoustic-sensing-of-bacterium-substratum-interface
 s.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>KBC / UCMR Seminar<br /> <br /> <strong>Ada
 m Olsson</strong><br /> McGill University\, Canada<br /> <br /> Title:<br 
 /> '<strong>Acoustic Sensing of Bacterium-Substratum Interfaces</strong>'<
 br /> <br /> Room: KB3B3\, KBC<br /> <br /> Host: Madeleine Ramstedt<br />
  <br /> Abstract:<br /> Acoustic Sensing of Bacterium-Substratum Interface
 s<br /> Adam L.J. Olsson<br /> McGill University<br /> &nbsp\;<br /> Bacte
 rial adhesion to surfaces and subsequent biofilm formation is an important
  phenomenon in many areas including\, amongst others\, biomedical engineer
 ing\, food processing and water treatment. &nbsp\;Since biofilms essential
 ly originate from only a few initial bacterial colonizers\, understanding 
 the mechanisms governing the initial bacterial adhesion event may help des
 igning surfaces with the ability to manipulate biofilm formation.<br /> <b
 r /> This presentation explores the possibilities to utilize a quartz crys
 tal microbalance with dissipation monitoring (QCM-D) to acoustically sense
  the mechanical properties of the bacterium-surface interface. The QCM-D i
 s generally considered a mass balance\, where a negative shift in the reso
 nance frequency of a quartz crystal sensor is proportional to attached mas
 s. However\, in the case of bacterial adhesion\, the surface attached bact
 erium possesses a resonance frequency that couples to the oscillation of t
 he sensor surface. The resulting frequency shift of this “coupled resonanc
 e” is either negative or positive\, depending on the ratio between QCM-D r
 esonance frequency and the bacterium resonance frequency which\, in turn\,
  is determined by its mass and surface contact stiffness. Thus\, analyzing
  bacterial adhesion in QCM-D within the context of “coupled resonance” off
 ers a unique opportunity to monitor mechanical properties of bacterium-sur
 face contacts.<br /> <br /> Since the quartz sensor is mounted in a temper
 ature controlled flow module\, and because change in resonance frequency o
 f the sensor is monitored in real time\, it possible to follow dynamic cha
 nges of the bacterium-surface contact during both the initial adhesion eve
 nt as well as during subsequent biofilm growth. Another important aspect o
 f the method is that the stiffness\, which is related to bond strength\, i
 s investigated without detaching the bacteria from the surface\; hence the
  method is non-destructive.<br /> &nbsp\;<br /> &nbsp\;</p>
END:VEVENT
BEGIN:VEVENT
UID:20141024T130000UTC-ff404c@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p><br /><strong>National and International Seminar Series</str
 ong></p>\n<p>Speaker:<br /><strong>Pierre-Yves Lozach</strong><br />Dept o
 f Infectious Diseases\, Virology\, Univ.Hospital Heidelberg\, Germany</p>
 \n<p>Title:<br /><strong>Bunyaviruses: host-to-host and cell-to-cell</stro
 ng></p>\n<p>Host: Anna Överby\, ClinMi</p>\n<p>&nbsp\;</p>\n<p>Room:&nbsp\
 ; Betula Lecture Hall\, Bldg 6M\, NUS</p>
DTSTART;TZID=Europe/Stockholm:20141024T150000
DTEND;TZID=Europe/Stockholm:20141024T160000
SUMMARY:Nat. and Internat Seminar Series - Pierre-Yves Lozach: Bunyaviruses
 : host-to-host and cell-to-cell
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 370-nat-and-internat-seminar-series-pierre-yves-lozach-bunyaviruses-host-t
 o-host-and-cell-to-cell.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p><br /><strong>National and International Se
 minar Series</strong></p>\n<p>Speaker:<br /><strong>Pierre-Yves Lozach</st
 rong><br />Dept of Infectious Diseases\, Virology\, Univ.Hospital Heidelbe
 rg\, Germany</p>\n<p>Title:<br /><strong>Bunyaviruses: host-to-host and ce
 ll-to-cell</strong></p>\n<p>Host: Anna Överby\, ClinMi</p>\n<p>&nbsp\;</p>
 \n<p>Room:&nbsp\; Betula Lecture Hall\, Bldg 6M\, NUS</p>
END:VEVENT
BEGIN:VEVENT
UID:20141028T141500UTC-c417cb@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>Department of Medical Biochemistry and Biophysics</p>\n<p>Se
 minar Series</p>\n<p><strong>Speaker:<br />Dr. Esther Bullitt<br /></stron
 g>Dept. of Physiology &amp\; Biophysics\, Boston University School of Medi
 cine\, Boston\, MA\, USA.</p>\n<p>Title:</p>\n<p><strong>'Assembly Interme
 diates of the Shigella Type III Secretion Apparatus: Nascent and Primed Sy
 ringe Tips'</strong></p>\n<p>Hosts: Bernt Eric Uhlin &amp\; Magnus Anderss
 on</p>\n<p>Room KB3A9\,&nbsp\; Lilla hörsalen\, KBC</p>
DTSTART;TZID=Europe/Stockholm:20141028T151500
DTEND;TZID=Europe/Stockholm:20141028T161500
SUMMARY:Esther Bullitt: Assembly Intermediates of the Shigella Type III Sec
 retion Apparatus: Nascent and Primed Syringe Tips
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 373-esther-bullitt-assembly-intermediates-of-the-shigella-type-iii-secreti
 on-apparatus-nascent-and-primed-syringe-tips.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>Department of Medical Biochemistry and Biop
 hysics</p>\n<p>Seminar Series</p>\n<p><strong>Speaker:<br />Dr. Esther Bul
 litt<br /></strong>Dept. of Physiology &amp\; Biophysics\, Boston Universi
 ty School of Medicine\, Boston\, MA\, USA.</p>\n<p>Title:</p>\n<p><strong>
 'Assembly Intermediates of the Shigella Type III Secretion Apparatus: Nasc
 ent and Primed Syringe Tips'</strong></p>\n<p>Hosts: Bernt Eric Uhlin &amp
 \; Magnus Andersson</p>\n<p>Room KB3A9\,&nbsp\; Lilla hörsalen\, KBC</p>
END:VEVENT
BEGIN:VEVENT
UID:20141030T140000UTC-fe43fa@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p><strong>Next generation tools for studying UPEC pathogenesis
 </strong></p>\n<p>Speaker: MD/PhD Swaine Chen\, Singapore NRF Fellow\, Nat
 ional University of Singapore and Genome Institute of Singapore\, Singapor
 e.</p>\n<p>Title: '<strong>Next generation tools for studying UPEC pathoge
 nesis</strong>'</p>\n<p>Room: Major Groove</p>\n<p>Hosts: Fredrik Almqvist
  and Sven Bergström&nbsp\;</p>\n<p>Abstract: Urinary tract infections (UTI
 s) are extremely common infections affecting half of all women and contrib
 uting greatly to antibiotic prescriptions and therefore bacterial antibiot
 ic resistance. Most UTIs are caused by uropathogenic Escherichia coli (UPE
 C). The study of how UPEC cause UTIs is greatly facilitated by many geneti
 c and molecular tools available for E. coli in general. However\, these to
 ols are usually developed in and for cloning or lab-adapted strains of E. 
 coli\, and they are sometimes not usable or not efficient in disease-causi
 ng clinical isolates such as UPEC.</p>\n<p>My lab has developed two new to
 ols with clinical strains in mind to improve our ability to study UTI. The
  first improves our ability to manipulate the UPEC chromosome. We have dev
 eloped a general and modular negative selection (counterselection) system 
 that functions without optimization in multiple clinical isolates of E. co
 li and Salmonella. Furthermore\, this system functions up to 1000x better 
 than all other reported systems in lab strains of E. coli. This system now
  enables the convenient creation of definitive genetic constructs directly
  in UPEC.</p>\n<p>The second project improves our ability to detect UPEC d
 uring infection. We have designed a new GFP protein which we term vGFP tha
 t demonstrates a 30-50% improvement in bulk brightness while simultaneousl
 y enabling rational control of dimerization state. vGFP is therefore a bet
 ter chromosomal reporter than other GFP variants and should improve our de
 tection sensitivity of UPEC\, which is paramount for tracking UPEC as they
  move through minor niches during infection.</p>\n<p>Together these tools 
 improve our ability to translate our mouse studies into human disease. I w
 ill conclude with our plans for performing niche-specific\, single-cell re
 solved\, simultaneous host and pathogen transcriptional profiling in direc
 t UTI samples. In the future\, this will hopefully allow us to do a full g
 enomic translation of our lab studies into knowledge about human disease.<
 /p>
DTSTART;TZID=Europe/Stockholm:20141030T150000
DTEND;TZID=Europe/Stockholm:20141030T160000
SUMMARY:Seminar - Swaine Chen: Next generation tools for studying UPEC path
 ogenesis
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 368-seminar-swaine-chen-next-generation-tools-for-studying-upec-pathogenes
 is.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p><strong>Next generation tools for studying 
 UPEC pathogenesis</strong></p>\n<p>Speaker: MD/PhD Swaine Chen\, Singapore
  NRF Fellow\, National University of Singapore and Genome Institute of Sin
 gapore\, Singapore.</p>\n<p>Title: '<strong>Next generation tools for stud
 ying UPEC pathogenesis</strong>'</p>\n<p>Room: Major Groove</p>\n<p>Hosts:
  Fredrik Almqvist and Sven Bergström&nbsp\;</p>\n<p>Abstract: Urinary trac
 t infections (UTIs) are extremely common infections affecting half of all 
 women and contributing greatly to antibiotic prescriptions and therefore b
 acterial antibiotic resistance. Most UTIs are caused by uropathogenic Esch
 erichia coli (UPEC). The study of how UPEC cause UTIs is greatly facilitat
 ed by many genetic and molecular tools available for E. coli in general. H
 owever\, these tools are usually developed in and for cloning or lab-adapt
 ed strains of E. coli\, and they are sometimes not usable or not efficient
  in disease-causing clinical isolates such as UPEC.</p>\n<p>My lab has dev
 eloped two new tools with clinical strains in mind to improve our ability 
 to study UTI. The first improves our ability to manipulate the UPEC chromo
 some. We have developed a general and modular negative selection (counters
 election) system that functions without optimization in multiple clinical 
 isolates of E. coli and Salmonella. Furthermore\, this system functions up
  to 1000x better than all other reported systems in lab strains of E. coli
 . This system now enables the convenient creation of definitive genetic co
 nstructs directly in UPEC.</p>\n<p>The second project improves our ability
  to detect UPEC during infection. We have designed a new GFP protein which
  we term vGFP that demonstrates a 30-50% improvement in bulk brightness wh
 ile simultaneously enabling rational control of dimerization state. vGFP i
 s therefore a better chromosomal reporter than other GFP variants and shou
 ld improve our detection sensitivity of UPEC\, which is paramount for trac
 king UPEC as they move through minor niches during infection.</p>\n<p>Toge
 ther these tools improve our ability to translate our mouse studies into h
 uman disease. I will conclude with our plans for performing niche-specific
 \, single-cell resolved\, simultaneous host and pathogen transcriptional p
 rofiling in direct UTI samples. In the future\, this will hopefully allow 
 us to do a full genomic translation of our lab studies into knowledge abou
 t human disease.</p>
END:VEVENT
BEGIN:VEVENT
UID:20141121T140000UTC-ad5fde@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p><strong>National and International Seminar Series 2014</stro
 ng></p>\n<p>Speaker:</p>\n<p><strong>Jose Perez Ortin</strong><br />Univer
 sity of Valencia\, Spain<br /><br />Title:<br /><strong>Genome-wide studie
 s of yeast mRNA turnover</strong><br /><br />Host: Tracy Nissan\, Molecula
 r Biology<br /><br />Room: Lecture hall Betula\, bldg 6M</p>
DTSTART;TZID=Europe/Stockholm:20141121T150000
DTEND;TZID=Europe/Stockholm:20141121T160000
SUMMARY:Nat and Internat Seminar Series - Jose Perez Ortin: Genome-wide stu
 dies of yeast mRNA turnover
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 375-nat-and-internat-seminar-series-jose-perez-ortin-genome-wide-studies-o
 f-yeast-mrna-turnover.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p><strong>National and International Seminar 
 Series 2014</strong></p>\n<p>Speaker:</p>\n<p><strong>Jose Perez Ortin</st
 rong><br />University of Valencia\, Spain<br /><br />Title:<br /><strong>G
 enome-wide studies of yeast mRNA turnover</strong><br /><br />Host: Tracy 
 Nissan\, Molecular Biology<br /><br />Room: Lecture hall Betula\, bldg 6M<
 /p>
END:VEVENT
BEGIN:VEVENT
UID:20141128T140000UTC-cfcdd9@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>National and International Seminar Series 2014</p>\n<p>Speak
 er: <br /><strong>Matthias Gunzer</strong><br />University of Essen\, Duis
 burg\, Essen</p>\n<p>Title:<br /><strong>Immune Dynamics</strong></p>\n<p>
 Host: Constantin Urban\, MIMS</p>\n<p><strong>NOTE ROOM:</strong><br /><st
 rong>Lecture room E04 Unod R1</strong></p>
DTSTART;TZID=Europe/Stockholm:20141128T150000
DTEND;TZID=Europe/Stockholm:20141128T160000
SUMMARY:Nat and Internat Seminar Series - Matthias Gunzer: Immune Dynamics
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 374-nat-and-internat-seminar-series-matthias-gunzer-immune-dynamics.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>National and International Seminar Series 2
 014</p>\n<p>Speaker: <br /><strong>Matthias Gunzer</strong><br />Universit
 y of Essen\, Duisburg\, Essen</p>\n<p>Title:<br /><strong>Immune Dynamics<
 /strong></p>\n<p>Host: Constantin Urban\, MIMS</p>\n<p><strong>NOTE ROOM:<
 /strong><br /><strong>Lecture room E04 Unod R1</strong></p>
END:VEVENT
BEGIN:VEVENT
UID:20141102T141500UTC-564417@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>Department of Medical Biochemistry and Biophysics<br />Semin
 ar Series 2014</p>\n<p>Speaker:</p>\n<p><strong>Andres Floto</strong><br /
 >Cambridge Institute for Medical Research\, University of Cambridge\, and 
 Cambridge Centre for Lung Infection\, Papworth Hospital\, Cambridge\, UK.<
 /p>\n<p>Title:<br /><strong>The role of nerve growth factor in immunity to
  Staphylococcus aureus</strong></p>\n<p><br />Place: Lecture Hall KB3A9 – 
 KBC building\, 3rd floor</p>\n<p>Host: Tor Ny<br />E-mail: <span id='cloak
 f521d192c563e353b903459e800b47ec'>This email address is being protected fr
 om spambots. You need JavaScript enabled to view it.</span><script type='t
 ext/javascript'>
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DTSTART;TZID=Europe/Stockholm:20141202T151500
DTEND;TZID=Europe/Stockholm:20141202T161500
SUMMARY:Seminar - Andres Floto: The role of nerve growth factor in immunity
  to Staphylococcus aureus
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 377-seminar-andres-floto-the-role-of-nerve-growth-factor-in-immunity-to-st
 aphylococcus-aureus.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>Department of Medical Biochemistry and Biop
 hysics<br />Seminar Series 2014</p>\n<p>Speaker:</p>\n<p><strong>Andres Fl
 oto</strong><br />Cambridge Institute for Medical Research\, University of
  Cambridge\, and Cambridge Centre for Lung Infection\, Papworth Hospital\,
  Cambridge\, UK.</p>\n<p>Title:<br /><strong>The role of nerve growth fact
 or in immunity to Staphylococcus aureus</strong></p>\n<p><br />Place: Lect
 ure Hall KB3A9 – KBC building\, 3rd floor</p>\n<p>Host: Tor Ny<br />E-mail
 : <span id='cloakf521d192c563e353b903459e800b47ec'>This email address is b
 eing protected from spambots. You need JavaScript enabled to view it.</spa
 n><script type='text/javascript'>
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 3e353b903459e800b47ec').innerHTML = ''\;
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END:VEVENT
BEGIN:VEVENT
UID:20150123T123000UTC-b1bd2a@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p><strong>UCMR- Molecular Biology - Extra seminar</strong><br 
 /><br /></p>\n<p>Speaker:<br /><strong>Andrew Darwin</strong><br />Departm
 ent of Microbiology\, NYU Langone Medical Center\, NY\, USA</p>\n<p>Title:
 <br /><strong>Surviving secretion: the Psp stress response of <em>Yersinia
  enterocolitica</em></strong></p>\n<p>Host: Matthew Francis<br />For more 
 information on Andrew Darwin's research follow the link:<br /><a href='htt
 p://www.ncbi.nlm.nih.gov/pubmed/?term=Darwin%20AJ[Author]&amp\;cauthor=tru
 e&amp\;cauthor_uid=23853578'>http://www.ncbi.nlm.nih.gov/pubmed/?term=Darw
 in%20AJ[Author]&amp\;cauthor=true&amp\;cauthor_uid=23853578</a></p>\n<p>Ro
 om Thymine\, Department of Molecular Biology\, Bldg 6K/L\, floor1</p>
DTSTART;TZID=Europe/Stockholm:20150123T133000
DTEND;TZID=Europe/Stockholm:20150123T143000
SUMMARY:UCMR-Molecular Biology - Extra seminar: Andrew Darwin
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 380-ucmr-molecular-biology-extra-seminar-andrew-darwin.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p><strong>UCMR- Molecular Biology - Extra sem
 inar</strong><br /><br /></p>\n<p>Speaker:<br /><strong>Andrew Darwin</str
 ong><br />Department of Microbiology\, NYU Langone Medical Center\, NY\, U
 SA</p>\n<p>Title:<br /><strong>Surviving secretion: the Psp stress respons
 e of <em>Yersinia enterocolitica</em></strong></p>\n<p>Host: Matthew Franc
 is<br />For more information on Andrew Darwin's research follow the link:<
 br /><a href='http://www.ncbi.nlm.nih.gov/pubmed/?term=Darwin%20AJ[Author]
 &amp\;cauthor=true&amp\;cauthor_uid=23853578'>http://www.ncbi.nlm.nih.gov/
 pubmed/?term=Darwin%20AJ[Author]&amp\;cauthor=true&amp\;cauthor_uid=238535
 78</a></p>\n<p>Room Thymine\, Department of Molecular Biology\, Bldg 6K/L\
 , floor1</p>
END:VEVENT
BEGIN:VEVENT
UID:20150123T140000UTC-87fd2f@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p><strong>National and International Seminar Series Spring 201
 5</strong></p>\n<p>Speaker:<br /><strong>Bernhard Singer</strong><br />Ins
 titute of Anatomy\, University Hospital Essen\, Germany</p>\n<p>Title:<br 
 /><strong>CEACAMs (CEA-related Cell Adhesion Molecules): multifunctional r
 eceptors with therapeutic potential to combat inflammation\, infection and
  cancer.</strong></p>\n<p>Host: Marene Landström</p>\n<p> </p>\n<p>Room: H
 örsal B\, Unod T08\, NUS</p>\n<p><a href='images/stories/documents/T_9_NUS
 _Karta_map.jpg' target='_blank' class='wf_file'><span class='wf_file_text'
 >How to find the Hörsal B</span></a></p>
DTSTART;TZID=Europe/Stockholm:20150123T150000
DTEND;TZID=Europe/Stockholm:20150123T160000
SUMMARY:Nat.and Internat. Seminar Series - Bernhard Singer
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 378-nat-and-internat-seminar-series-bernhard-singer-ceacams-cea-related-ce
 ll-adhesion-molecules-multifunctional-receptors-with-therapeutic-potential
 -to-combat-inflammation-infection-and-cancer.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p><strong>National and International Seminar 
 Series Spring 2015</strong></p>\n<p>Speaker:<br /><strong>Bernhard Singer<
 /strong><br />Institute of Anatomy\, University Hospital Essen\, Germany</
 p>\n<p>Title:<br /><strong>CEACAMs (CEA-related Cell Adhesion Molecules): 
 multifunctional receptors with therapeutic potential to combat inflammatio
 n\, infection and cancer.</strong></p>\n<p>Host: Marene Landström</p>\n<p>
  </p>\n<p>Room: Hörsal B\, Unod T08\, NUS</p>\n<p><a href='images/stories/
 documents/T_9_NUS_Karta_map.jpg' target='_blank' class='wf_file'><span cla
 ss='wf_file_text'>How to find the Hörsal B</span></a></p>
END:VEVENT
BEGIN:VEVENT
UID:20150130T083000UTC-68a70f@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>STINT Workshop at Department of Chemistry and UCMR<br /> <br
  /> <strong>9:30-10:00</strong><br /> Speaker<br /> <strong>Prof Thereza A
 . Soares</strong><br /> Department of Fundamental Chemistry\, Federal Univ
 ersity of Pernambuco\, Brazil<br /> <br /> Title:<br /> <strong>Molecular 
 Models of Lipopolysaccharide Membranes</strong><br /> -----------</p>\n<p>
 10:15-10:45</p>\n<p>Speaker:<br /> <strong>Alexandre José Macedo</strong><
 br /> Department of Pharmacy\, Federal University of Rio Grande do Sul\, B
 razil<br /> <br /> Title:<br /> <strong>Brazilian biodiversity compounds a
 gainst bacterial adhesion</strong><br /> <br /> <br /> Host:<br /> Madelei
 ne Ramstedt<br /> Room: KB3A9<br /> <br /> <a href='http://www.kbc.umu.se/
 images/stories/STINT_Thereza_Soares_and_Alexandre_Macedo_20151.pdf' target
 ='_blank'><strong>Abstracts (pdf-file)</strong></a><br /> <br /> <strong>M
 ore about Thereza Soares</strong><br /> http://www.dqf.ufpe.br/index.php?o
 ption=com_content&amp\;view=article&amp\;id=337%3Aprofa-thereza-soares&amp
 \;catid=1&amp\;Itemid=247<br /> <br /> <br /> <strong>More about José Mace
 do:</strong><br /> http://www.ufrgs.br/lbdim/inicio/inicio-en/<br /> </p>
DTSTART;TZID=Europe/Stockholm:20150130T093000
DTEND;TZID=Europe/Stockholm:20150130T113000
SUMMARY:STINT Symposium - Thereza A. Soares and Alexandre José Macedo
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 381-stint-symposium-thereza-a-soares-and-alexandre-jose-macedo.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>STINT Workshop at Department of Chemistry a
 nd UCMR<br /> <br /> <strong>9:30-10:00</strong><br /> Speaker<br /> <stro
 ng>Prof Thereza A. Soares</strong><br /> Department of Fundamental Chemist
 ry\, Federal University of Pernambuco\, Brazil<br /> <br /> Title:<br /> <
 strong>Molecular Models of Lipopolysaccharide Membranes</strong><br /> ---
 --------</p>\n<p>10:15-10:45</p>\n<p>Speaker:<br /> <strong>Alexandre José
  Macedo</strong><br /> Department of Pharmacy\, Federal University of Rio 
 Grande do Sul\, Brazil<br /> <br /> Title:<br /> <strong>Brazilian biodive
 rsity compounds against bacterial adhesion</strong><br /> <br /> <br /> Ho
 st:<br /> Madeleine Ramstedt<br /> Room: KB3A9<br /> <br /> <a href='http:
 //www.kbc.umu.se/images/stories/STINT_Thereza_Soares_and_Alexandre_Macedo_
 20151.pdf' target='_blank'><strong>Abstracts (pdf-file)</strong></a><br />
  <br /> <strong>More about Thereza Soares</strong><br /> http://www.dqf.uf
 pe.br/index.php?option=com_content&amp\;view=article&amp\;id=337%3Aprofa-t
 hereza-soares&amp\;catid=1&amp\;Itemid=247<br /> <br /> <br /> <strong>Mor
 e about José Macedo:</strong><br /> http://www.ufrgs.br/lbdim/inicio/inici
 o-en/<br /> </p>
END:VEVENT
BEGIN:VEVENT
UID:20150206T140000UTC-c43135@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>National and International Seminar Series 2015</p>\n<p> </p>
 \n<p>Speaker</p>\n<p><strong>Cristina Prat Aymerich</strong> <br />Hospita
 l Universitari Germans Trias i Pujol/ Universitat Autònoma de Barcelona</p
 >\n<p> </p>\n<p>Title:</p>\n<p><strong>Bridging clinics and research in in
 fectious diseases</strong></p>\n<p>Host:Olena Rzhepishevska\, Clinical Mic
 robiology</p>\n<p>Room: Betula bldg 6M\, NUS</p>
DTSTART;TZID=Europe/Stockholm:20150206T150000
DTEND;TZID=Europe/Stockholm:20150206T150000
SUMMARY:Nat. and Internat Seminar - Cristina Prat Aymerich: Bridging clinic
 s and research in infectious diseases
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 382-nat-and-internat-seminar-cristina-prat-aymerich-bridging-clinics-and-r
 esearch-in-infectious-diseases.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>National and International Seminar Series 2
 015</p>\n<p> </p>\n<p>Speaker</p>\n<p><strong>Cristina Prat Aymerich</stro
 ng> <br />Hospital Universitari Germans Trias i Pujol/ Universitat Autònom
 a de Barcelona</p>\n<p> </p>\n<p>Title:</p>\n<p><strong>Bridging clinics a
 nd research in infectious diseases</strong></p>\n<p>Host:Olena Rzhepishevs
 ka\, Clinical Microbiology</p>\n<p>Room: Betula bldg 6M\, NUS</p>
END:VEVENT
BEGIN:VEVENT
UID:20150213T140000UTC-dfcf27@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>National and International Seminar Series 2015</p>\n<p>Speak
 er:<br /><strong>Prof. Kenn Gerdes</strong><br />Department of Biology\, U
 niversity of Copenhagen</p>\n<p>Title:<br /><strong>Magic Spot and Bacteri
 al Persistence</strong></p>\n<p>Host: Vasili Hauryliuk\, MolBiol<br />Room
 : Hörsal B\, UnodT 9\, NUS</p>
DTSTART;TZID=Europe/Stockholm:20150213T150000
DTEND;TZID=Europe/Stockholm:20150213T160000
SUMMARY:Nat and Internat Seminar Series - Kenn Gerdes: Magic Spot and Bacte
 rial Persistence
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 383-nat-and-internat-seminar-series-kenn-gerdes-magic-spot-and-bacterial-p
 ersistence.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>National and International Seminar Series 2
 015</p>\n<p>Speaker:<br /><strong>Prof. Kenn Gerdes</strong><br />Departme
 nt of Biology\, University of Copenhagen</p>\n<p>Title:<br /><strong>Magic
  Spot and Bacterial Persistence</strong></p>\n<p>Host: Vasili Hauryliuk\, 
 MolBiol<br />Room: Hörsal B\, UnodT 9\, NUS</p>
END:VEVENT
BEGIN:VEVENT
UID:20150220T140000UTC-88eadd@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p><strong>National and International Seminar Series 2015</stro
 ng></p>\n<p>Speaker:<br /><strong>Silvia Nicolis</strong> <br />Department
  of Biotechnology and Biosciences University of Milano-Biocca\, Italy</p>
 \n<p><strong>Title:</strong> <br />The Sox2 transcription factor in brain 
 development and in neural tumors: genome-wide studies in neural stem cells
  <br /><br /><strong>Contact:</strong> Lena Gunhaga\, UCMM <br /><strong>R
 oom:</strong> Lecture Hall Betula\, Bldg 6M <br /><br /><strong>Abstract:<
 /strong><br /> Sox2 is a transcription factor essential for pluripotent st
 em cells\, also active in stem cells of different tissues. Silvia Nicolis'
  group investigates the role of Sox2 in the development of the nervous sys
 tem\, in particular of the brain\, analysing the molecular mechanisms of i
 ts action. In parallel\, they also study the possible role of Sox2 in brai
 n tumors. One aim of their studies is to better understand\, through the f
 unctional investigation of Sox2\, its role in the hereditary pathology of 
 the nervous system and in brain tumors\, with possible implications for th
 erapy.</p>
DTSTART;TZID=Europe/Stockholm:20150220T150000
DTEND;TZID=Europe/Stockholm:20150220T150000
SUMMARY:Nat. and Internat. Seminar Series. The Sox2 transcription factor in
  brain development and in neural tumors: genome-wide studies in neural ste
 m cells
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 384-nat-and-internat-seminar-series-the-sox2-transcription-factor-in-brain
 -development-and-in-neural-tumors-genome-wide-studies-in-neural-stem-cells
 .html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p><strong>National and International Seminar 
 Series 2015</strong></p>\n<p>Speaker:<br /><strong>Silvia Nicolis</strong>
  <br />Department of Biotechnology and Biosciences University of Milano-Bi
 occa\, Italy</p>\n<p><strong>Title:</strong> <br />The Sox2 transcription 
 factor in brain development and in neural tumors: genome-wide studies in n
 eural stem cells <br /><br /><strong>Contact:</strong> Lena Gunhaga\, UCMM
  <br /><strong>Room:</strong> Lecture Hall Betula\, Bldg 6M <br /><br /><s
 trong>Abstract:</strong><br /> Sox2 is a transcription factor essential fo
 r pluripotent stem cells\, also active in stem cells of different tissues.
  Silvia Nicolis' group investigates the role of Sox2 in the development of
  the nervous system\, in particular of the brain\, analysing the molecular
  mechanisms of its action. In parallel\, they also study the possible role
  of Sox2 in brain tumors. One aim of their studies is to better understand
 \, through the functional investigation of Sox2\, its role in the heredita
 ry pathology of the nervous system and in brain tumors\, with possible imp
 lications for therapy.</p>
END:VEVENT
BEGIN:VEVENT
UID:20150227T140000UTC-32b13c@http://www.ucmr.umu.se/
DTSTAMP:20260604T234055Z
CATEGORIES:Seminar
DESCRIPTION:<p>National and International Seminar Series 2015</p>\n<p>Speak
 er:</p>\n<p>Irene Miguel Aliaga<br />Clinical Sciences Center\, MRC\, UK</
 p>\n<p>Title:<br />Hungry Brains and Clever Guts</p>\n<p>Host: Cedric and 
 Alexandros\, UCMM</p>\n<p> </p>\n<p>Room: Betula \, Bldg 6M</p>
DTSTART;TZID=Europe/Stockholm:20150227T150000
DTEND;TZID=Europe/Stockholm:20150227T160000
SUMMARY:Nat. and Internat Seminar Series - Irene Miguel Aliaga: Hungry Brai
 ns and Clever Guts
URL:http://www.ucmr.umu.se/about-ucmr/events/162-ucmr-calendar/164-seminar/
 385-nat-and-internat-seminar-series-irene-miguel-aliaga-hungry-brains-and-
 clever-guts.html
X-ALT-DESC;FMTTYPE=TEXT/HTML:<p>National and International Seminar Series 2
 015</p>\n<p>Speaker:</p>\n<p>Irene Miguel Aliaga<br />Clinical Sciences Ce
 nter\, MRC\, UK</p>\n<p>Title:<br />Hungry Brains and Clever Guts</p>\n<p>
 Host: Cedric and Alexandros\, UCMM</p>\n<p> </p>\n<p>Room: Betula \, Bldg 
 6M</p>
END:VEVENT
END:VCALENDAR
