| Anna Överby Tick borne encephalitis virus Tick borne encephalitis virus (TBEV) is an important emerging human pathogen. The virus infection causes a broad spectrum of symptoms ranging from mild infections to more severe symptoms such as meningitis, encephalitis, and hemorrhagic fever associated with high mortality rates. The severity of the symptoms is strain dependent. Whereas TBEV strains from Central Europe often cause milder disease, strains from Siberia and Far Eastern frequently lead to more severe symptoms. The molecular mechanism underlying this virus strain dependency remains elusive. Therefore, we are interested in identifying potential molecular strain differences and correlating them with pathogenicity. Specific antiviral drugs are still not available and treatment of patients is limited to supportive care only. Although an effective vaccine is available, the number of clinical TBE cases is increasing both in Sweden and all over Europe.  Read More (Anna Överby's group at MIMS) |
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Tick borne encephalitis virus and meningoencephalitis
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